Stable Ziyin Runchang Oral Liquid Pharmaceutical Composition for Nourishing Yin, Clearing Heat, Moistening Intestines and Laxative
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A technology of laxative, nourishing yin and clearing away heat, which is applied in the field of medicine and can solve the problems of high transportation costs and short storage time of fresh rehmannia glutinosa
Active Publication Date: 2021-07-27
BEIJING CHENG JI PHARMA
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[0012] CN1187998A (application number: 97100259.2) discloses a fresh rehmannia slice and its processing method. The method is to quickly dry the fresh rehmannia slices at a temperature below 100°C. The fresh rehmannia slices processed in this way not only retain the active ingredients of the fresh rehmannia glutinosa , and solve the technical problems of fresh rehmannia glutinosa short storage time and high transportation costs, the active ingredient content of stachyose is more than 40%, catalpol is more than 2.0%
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Embodiment 1
[0113] Example 1: Preparation of Nourishing Yin and Runchang Oral Liquid
[0114] (1) Take 1000g of Rehmannia glutinosa, add water to decoct twice, add 12 times the amount of water for the first time, decoct for 1.5 hours, add 8 times the amount of water for the second time, decoct for 1 hour;
[0115] (2) Combine the decoction, filter, add 6% activated carbon to the filtrate for decolorization, and centrifugally filter,
[0116] (3) The filtrate is concentrated under reduced pressure to 1000ml, refrigerated for 48 hours, centrifuged, filtered (to obtain 1000m liquid medicine), filled, sterilized, and ready to be obtained.
Embodiment 2
[0117] Example 2: Preparation of Nourishing Yin and Runchang Oral Liquid
[0118] (1) Take 1000g of rehmannia glutinosa, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 10 times the amount of water for the second time, decoct for 0.5 hours;
[0119] (2) Combine the decoction, filter, add 10% activated carbon to the filtrate for decolorization, and centrifugally filter,
[0120] (3) The filtrate is concentrated under reduced pressure to 1000ml, refrigerated for 60 hours, centrifuged, filtered (to obtain 1000m liquid medicine), filled, sterilized, and obtained.
Embodiment 3
[0121] Example 3: Preparation of Nourishing Yin and Runchang Oral Liquid
[0122] (1) Take 1000g of Rehmannia glutinosa, add water to decoct twice, add 15 times the amount of water for the first time, decoct for 1 hour, add 5 times the amount of water for the second time, decoct for 1.5 hours;
[0123] (2) Merge the decoction, filter, add 4% active carbon to the filtrate for decolorization, centrifugal filtration,
[0124] (3) The filtrate is concentrated under reduced pressure to 1000ml, refrigerated for 40 hours, centrifuged, filtered (to obtain 1000m liquid medicine), filled, sterilized, and obtained.
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Abstract
The invention relates to a stable nourishing yin and moistening oral liquid medicinal composition for laxative use. Specifically, the pharmaceutical composition is prepared from Rehmannia glutinosa in the form of oral liquid prepared by heating and extracting with water. It also relates to the preparation method of the pharmaceutical composition, its detection method and its therapeutic use. The nourishing Yin and Runchang oral liquid of the present invention can be clinically used for the auxiliary treatment of dry stool, poor defecation, dry mouth and throat, red tongue and less fluid due to internal heat syndrome due to yin deficiency. It is especially suitable for middle-aged and elderly habitual constipation, poor defecation in children, poor defecation caused by long-term bed rest, poor defecation caused by long-term use of drugs such as analgesics, anticonvulsants, antacids, antihypertensive drugs, etc. Poor defecation after chemotherapy, postpartum, postoperative poor defecation, incomplete intestinal obstruction, intestinal adhesions; clinically applicable clinical departments include but are not limited to: traditional Chinese medicine, gastroenterology, anorectal, geriatrics, obstetrics and gynecology Wait.
Description
technical field [0001] The invention belongs to the technical field of medicine, and relates to a pharmaceutical composition with functions of nourishing yin, clearing away heat, moistening intestines and defecating, in particular to a pharmaceutical composition of nourishing yin and moistening intestines oral liquid, and also relates to a preparation method of the pharmaceutical composition. and their quality control methods. Background technique [0002] Constipation is the most common and therefore the most overlooked condition. In daily life, I often hear suggestions to solve constipation such as taking some laxatives. Most patients with constipation are caused by the lack of bifidobacteria in the intestines, especially the elderly, as the bifidobacteria in the intestines gradually decrease with age, they are very prone to constipation. [0003] For this common but not life-threatening disease, constipation has become a major concern for doctors. Because constipation ...
Claims
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