The invention belongs to the technical field of traditional Chinese medicine, and discloses preparation and preliminary pharmaceutical evaluation methods of a compound qi-tonifying and intestine-moistening capsule. The compound qi-tonifying and intestine-moistening capsule is composed of fructus cannabis, semen pruni, raw radix astragali, radix codonopsis, fructus aurantii immaturus and radix polygonati officinalis. The preparation method of the compound qi-tonifying and intestine-moistening capsule comprises the following steps of: adding the fructus cannabis fine powder and the semen pruni fine powder into dry extract powder extracted from the raw radix astragali, the radix codonopsis, the radix polygonati officinalis and the fructus aurantii immaturus, granulating together, and after adding pectin, filling into a capsule shell so as to obtain the compound qi-tonifying and intestine-moistening capsule. According to the invention, the pectin is added, the pectin is basically not absorbed after entering the digestive tract, and the pectin forms jelly after absorbing water, so that not only can intestinal moisture be maintained, but also the volume of excreta in the large intestine can be increased so as to stimulate intestinal peristalsis to generate awareness of defecation and take the effect of promoting the medicine effect; and the compound qi-tonifying and intestine-moistening capsule has the effects of tonifying qi, nourishing yin, increasing liquid, moistening dryness, promoting the circulation of qi, removing stagnation and relaxing bowel, is conformity with constipation of gerontal patients, which is caused by deficiency of qi and yin, not only can relax the bowels, but also can improve the overall function of the patients, and takes the effect of treating diseases and solving the root cause.