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A sofi-based ultra-high resolution plane wave ultrasound imaging method

An ultrasonic imaging method and plane wave technology, applied in ultrasonic/sonic/infrasonic diagnosis, sonic diagnosis, infrasonic diagnosis, etc., can solve problems such as limiting the spatial resolution of ultrasonic imaging

Active Publication Date: 2020-10-30
SHANGHAI UNIV
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  • Claims
  • Application Information

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Problems solved by technology

Considering that SOFI has a nonlinear response to brightness, this limits the spatial resolution of ultrasound imaging based on SOFI methods to some extent

Method used

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  • A sofi-based ultra-high resolution plane wave ultrasound imaging method
  • A sofi-based ultra-high resolution plane wave ultrasound imaging method
  • A sofi-based ultra-high resolution plane wave ultrasound imaging method

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Embodiment Construction

[0030] Preferred embodiments of the present invention are described in detail as follows:

[0031] (1) see figure 1 , based on SOFI ultra-high resolution plane wave ultrasonic imaging method, in order to verify the feasibility of this method, taking the ultrasonic plane wave simulation image as an example, the specific steps are as follows:

[0032] (2) Perform ultrasonic plane wave imaging through the Field II simulation platform, and obtain a set of plane wave ultrasonic images at different times. Each frame of image contains multiple point scatterers (microbubbles), which are randomly distributed in the imaging area; the specific simulation steps are as follows:

[0033] (1-1) Use the Field II simulation platform, after setting the relevant parameters, create a phantom, which contains multiple point scatterers at a depth of 30mm to 40mm, and use a single plane wave emission containing 192 array elements to scan the phantom , and the related parameters of the scan are show...

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Abstract

The invention discloses an ultrahigh-resolution ultrasonic plane wave imaging method based on SOFI. The method comprises the following steps: with the intervention of an ultrasonic contrast agent (micro-vesicle), conducting ultrasonic plane wave imaging on an imaged object, so that a group of ultrasonic plane wave images at different moments; conducting a filtering operation on all acquired ultrasonic plane wave images, so as to remove noise in the ultrasonic plane wave images; based on ultrasonic plane wave data, which just contains one micro-vesicle, in an imaging area, determining and calculating a transverse full width at half maximum FHWMx and a longitudinal full width at half maximum FHWMy, so as to obtain a transverse standard difference [gamma]x and a longitudinal standard difference [gamma]y, so that a point spread distribution model is generated; and finally, with the dynamic ultrasonic plane wave image obtained from filtering as input data, conducting calculating, so that anSOFI image of second-order (or high-order) balancing is obtained. With the application of the method provided by the invention, spatial resolution of the ultrasonic plane wave imaging can be greatlyimproved, and moreover, time resolution of the ultrasonic imaging can be also improved; and the ultrasonic plane wave imaging method is applicable to rapid ultrahigh-resolution ultrasonic imaging.

Description

technical field [0001] The invention relates to a super-resolution plane wave ultrasonic imaging method based on SOFI (Super-resolution Optical Fluctuation Imaging, super-resolution fluorescence fluctuation imaging). Specifically, with the intervention of ultrasound contrast agents (microbubbles), ultrasonic plane wave imaging is performed on the imaging object to obtain a set of plane wave ultrasonic images at different moments; for all acquired plane wave ultrasonic images, based on the Wiener filter (or other filters) to remove the noise contained in the plane wave ultrasonic image; based on the ultrasonic plane wave data of a single microbubble, through the measured transverse half maximum width x with vertical half-height width FHWM y Calculate the horizontal standard deviation δ x and longitudinal standard deviation δ y , based on this, a point spread distribution model is generated; finally, with the filtered dynamic ultrasonic plane wave image as input data, based o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B8/00G06T3/40
CPCA61B8/481A61B8/5215G06T3/4053
Inventor 刘欣吕明雷束月霞刘颖赵丽丽
Owner SHANGHAI UNIV
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