Drug for fungal skin disease and preparation method of drug

Abstract

The invention relates to a drug for a fungal skin disease and a preparation method of the drug. The drug comprises a soaking agent and a coating paste. The soaking agent is prepared from the followingcomponents in parts by weight: 1-3 parts of sulfur, 0.5-1 part of potassium permanganate, 1-2 parts of acetic acid, 3-5 parts of fresh ginger, 3-5 parts of garlic, 8-10 parts of willow barks, 1-3 parts of table salt and 14-20 parts of water; and the coating paste is prepared from the following components in parts by weight: 1-2 parts of 5-fluorouracil and 9-11 parts of vaseline. Each 100g of thesoaking agent is mixed with 0.8L warm water with the temperature being 35-45 DEG C, a clean towel is put into the soaking agent solution for soaking and is hot compressed at an affected part to exertthe efficacy of softening skin keratinocytes at the affected part and performing sterilization and disinfection; the fresh ginger can enable blood vessels to expand to promote body pore opening, the garlic is natural plant broad spectrum antibiotics, and after the operations are finished, the prepared coating paste is applied to the affected part; as the skin pores of the affected part open and the peripheral capillaries relax, the 5-fluorouracil in the coating paste more easily enters deep tissues in the local environment, so that fungi are killed at deep level without generating side effects and is difficult to recur.

Description

technical field [0001] The invention belongs to the technical field of medicines, in particular to medicines for treating fungal skin diseases. Background technique [0002] Fungal infection can be divided into superficial fungal infection and deep fungal infection. Superficial infection is caused by ringworm fungus invading the skin, hair, finger (toe) nail and other body surface parts. It has a high incidence rate and is less harmful, but It brings great troubles to life, work and study. Most skin diseases are accompanied by itching, pain, bleeding and other symptoms. Especially scratching is not very elegant, which will cause great discomfort and a certain inferiority complex. Deep fungal infection is caused by candida and cryptococcus invading internal organs and deep tissues, with low incidence and great harm. [0003] Commonly used antifungal drugs are divided into superficial fungal infection drugs according to the site of action: undecylenic acid, acetic acid, lacti...

AI Technical Summary

Problems solved by technology

[0003] Commonly used antifungal drugs are divided into superficial fungal infection drugs according to the site of action: undecylenic acid, acetic acid, lactic acid, salicylic acid, griseofulvin, clindamycin, clotrimazole, miconazole, econazole , bifonazole, ketoconazole, etc., due to the strong drug resistance of fungal skin diseases, acetic acid, salicylic acid alone or in combination, it is difficult to kill the fungus deeply, and it is easy to relapse

Anti-deep fungal infection drugs include flucytosine, amphotericin B, nystatin, erythromycin, mepamycin (mepatroxine, clotrimazine), fluconazole (diflucan, manifene) , Yilikang), itraconazole (Spiranox), etc., if anti-deep drugs such as flucytosine are directly applied to the affected area of ​​fungal skin diseases, the effect is very limited, such as injection of anti-deep drugs such as flucytosine, Toxic and side effects, causing bad effects on body organs