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Methods to prevent tissue colonization of pathogens and for treatment of biofilms on animal tissues

A biofilm, pathogen technology, applied in the fields of botanical equipment and methods, plant growth regulators, animal repellants, etc., can solve the problem of CAB products not being successful

Inactive Publication Date: 2018-06-08
REDUXX LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Consequently, most of the CAB products used were not commercially successful

Method used

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  • Methods to prevent tissue colonization of pathogens and for treatment of biofilms on animal tissues
  • Methods to prevent tissue colonization of pathogens and for treatment of biofilms on animal tissues
  • Methods to prevent tissue colonization of pathogens and for treatment of biofilms on animal tissues

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Embodiment Construction

[0037] A detailed description of embodiments of the disclosed method described below is given by way of example, and not meant to be limiting, with reference to the figures listed above. While certain embodiments have been shown and described in detail, it should be understood that various changes and modifications may be made without departing from the scope of the appended claims. The scope of the present disclosure is by no means limited to the number of constituent parts, their materials, their shapes, their relative arrangements, etc., and they are disclosed only as examples of embodiments of the present disclosure.

[0038] As a prelude to the detailed description, it should be noted that, as used in this specification and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the context clearly dictates otherwise. Some general definitions are provided for terms used herein. A "biofilm" is any group of microorganisms in which cells...

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Abstract

An antimicrobial product and methods of use are provided. The antimicrobial product includes a water-soluble antimicrobial organosilane (3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride)and various additional adjuvant compounds, including anti-inflammatory medications, antiseptics, penetrants and / or detergents. An example delivery system including a microcapsule encasing the productis also described. Methods of use include embedding a delivery system within an article, such as bandages, inserts or wound coverings, the microcapsule containing the product which is released by a mechanism and at a time particular to the intended use of the article. The methods include topically treating a biofilm infection on an animal tissue substrate by disrupting existing microbial biofilm growth, penetrating existing biofilms, thereby killing microbes, and also through providing residual bonded organosilane, then killing persister cell microbes that through degrees of dormancy have escaped being killed.

Description

[0001] background technical field [0002] The present disclosure relates generally to antimicrobial compounds having antimicrobial activity; in particular to topical treatment of biofilms in animals and humans, including the eyes, ear canal, skin and subcutaneous tissue, toenails, and infected wounds and abrasions Organosilane quaternary ammonium compounds for and other microbial pathogens. Background technique [0003] Since the discovery of microorganisms and their role in causing disease, the prevention and treatment of infections in humans and animals has become a public health goal. As a result of the germ theory of disease, great strides have been made in controlling the transmission, spread, and impact of disease-causing microorganisms. For example, simple techniques such as regular hand washing and thorough cleaning of hard surfaces can be very effective in preventing the spread of contact-borne diseases. One such approach is through the use of face masks designed...

Claims

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Application Information

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IPC IPC(8): A01N31/16A01N31/08A01N25/22
CPCA61L31/16A61K45/06A61L2300/404A61L2300/622A61K31/695A61K2300/00A61K9/50A61K47/20A61L15/20A61L15/44
Inventor C·希利亚德W·R·卡斯特
Owner REDUXX LLC