Use of chlorite to treat red blood cell diseases and indications mediated thereby
A chlorite, diabetes technology, applied in extracellular fluid diseases, metabolic diseases, blood diseases, etc., can solve problems such as no evidence of inhibition of AGE end-organ damage
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[0080] A preferred composition is WF10, eg, disclosed in US Patent No. 8,252,343 as an agent for the treatment of allergies, asthma and dermatitis.
[0081] WF10 is a sterile, pyrogen-free, 10% (w / v) dilute aqueous solution of the drug OXO-K993, which is analytically characterized as containing ionic chlorite (4.25%), chloride (2.0%), chlorate (1.5%), sulfate (0.7%) and sodium (4.0%) solution. Human clinical research has generated a large amount of safety evidence. When WF10 is infused at a daily dose of 0.5mL / kg for 5 consecutive days, followed by a 16-day drug-free interval, it constitutes a "cycle". In both regimens, patients received 6 cycles of treatment, and in another trial, patients received 4 cycles followed by maintenance every 6 weeks for up to 128 weeks. In any event, WF10 showed an excellent safety profile, with no steroid-like side effects, no immunosuppression, no antihistamine-like side effects, and no cardiovascular side effects.
[0082] WF10 has been shown...
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