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Pharmaceutical composition with anti-oxidation and immunoregulation effects and preparation method thereof

An immunoregulatory and antioxidative technology, applied in drug combinations, medical preparations containing active ingredients, antitumor drugs, etc., can solve the problem of limited immune protection, and achieve good immune regulation and antioxidant effects Good and easy to take effect

Inactive Publication Date: 2018-06-22
珠海经济特区天然药物研究所有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Among the existing natural antioxidants, tea (catechins, green tea, black tea and oolong tea) has the strongest antioxidant effect, and it is found that catechins and cloves also have certain immune protection effects, but their immune protection effects are relatively limited

Method used

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  • Pharmaceutical composition with anti-oxidation and immunoregulation effects and preparation method thereof
  • Pharmaceutical composition with anti-oxidation and immunoregulation effects and preparation method thereof
  • Pharmaceutical composition with anti-oxidation and immunoregulation effects and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0025] The pharmaceutical composition with antioxidant and immunoregulatory effects comprises the following raw materials in parts by weight: 25 parts of green tea, 45 parts of Gynostemma pentaphyllum, 20 parts of hawthorn, and 10 parts of auxiliary materials.

[0026] In this embodiment, the green tea is green tea, and the auxiliary material is starch, and the above pharmaceutical composition is made into tablets, such as figure 1 Shown, concrete preparation method step is as follows:

[0027] 1) Weigh each raw material according to the formula quantity, put all the raw materials except auxiliary materials into the extraction tank in turn, add 70% ethanol of 6 times the amount of medicinal materials, soak for 20 minutes, turn on the oil heater to heat up the oil, when the oil temperature reaches ℃ At 130°C, turn on the circulating pump for heating in an oil bath; when the boiling extract begins to boil, carry out the first reflux extraction, reflux extraction for 1.5 hours, s...

Embodiment 2

[0030] The pharmaceutical composition with antioxidant and immunoregulatory effects comprises the following raw materials in parts by weight: 15 parts of green tea, 55 parts of Gynostemma pentaphyllum, 15 parts of hawthorn, and 15 parts of auxiliary materials.

[0031] In this embodiment, the green tea is green tea, and the auxiliary materials are commonly used auxiliary materials for capsules such as microcrystalline cellulose, magnesium stearate, talcum powder, and sodium starch. The above pharmaceutical composition is made into capsules. The specific preparation method steps as follows:

[0032] 1) Weigh each raw material according to the formula quantity, put all raw materials except auxiliary materials into the extraction tank in turn, add 70% ethanol of 6 times the amount of medicinal materials, soak for 30 minutes, turn on the oil heater to heat up the oil, when the oil temperature reaches At 130°C, turn on the circulating pump for heating in an oil bath; when the boili...

Embodiment 3

[0035] The pharmaceutical composition with antioxidant and immunoregulatory effects comprises the following raw materials in parts by weight: 35 parts of green tea, 35 parts of Gynostemma pentaphyllum, 25 parts of hawthorn, and 5 parts of auxiliary materials.

[0036] In this embodiment, the green tea is green tea, and the auxiliary materials are powdered sugar and dextrin, and the above pharmaceutical composition is made into granules, and the specific steps of the preparation method are as follows:

[0037] 1) Weigh each raw material according to the formula amount, put all the raw materials except auxiliary materials into the extraction tank in turn, add 70% ethanol of 6 times the amount of medicinal materials, soak for 25 minutes, turn on the oil heater to heat the oil, when the oil temperature reaches At 130°C, turn on the circulating pump for heating in an oil bath; when the boiling extract begins to boil, carry out the first reflux extraction, reflux extraction for 1.5 h...

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Abstract

The invention discloses a pharmaceutical composition with anti-oxidation and immunoregulation effects and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine. The pharmaceutical composition comprises, by weight, 15-30 parts of green tea, 35-55 parts of gynostemma pentaphylla, 15-25 parts of hawthorn fruits and 5-15 parts of auxiliary materials. The preparation method comprises the following steps that all the raw materials except the auxiliary materials are put into an extraction tank and subjected to reflux extraction twice through the ethyl alcohol extraction technology; vacuum concentration is conducted on an extracting solution; the auxiliary materials are added and stirred to prepare a soft material or a mixed solution, and then the soft material or the mixed solution is processed into a clinically acceptable dosage form. The pharmaceutical composition takes green tea, hawthorn fruits and gynostemma pentaphylla as main raw materials, the content of active ingredients is relatively high, and the pharmaceutical composition is more convenient to take and has good immunoregulation and anti-oxidation effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition with anti-oxidation and immune regulation functions and a preparation method thereof. Background technique [0002] Oxidative stress is when the body is stimulated by exogenous or endogenous sources, the content of active molecules such as oxygen free radicals and nitrogen free radicals increases, and the oxidation reaction is accelerated. Once the body's ability to scavenge oxidation products is exceeded, the operating load of various systems in the body will increase , leading to normal metabolic disorders, inflammatory reactions, and various diseases, such as neurodegenerative diseases, diabetes, hypertension, atherosclerosis, etc. Therefore, resisting oxidative stress is a necessary means to protect the normal function of the body. In the study of anti-oxidative stress, many natural antioxidants can effectively reduce the ris...

Claims

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Application Information

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IPC IPC(8): A61K36/82A61P37/04A61P39/06A61P35/00
CPCA61K36/424A61K36/734A61K36/82A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 闫玉森闫蔚
Owner 珠海经济特区天然药物研究所有限公司
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