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Controllable-pressure bubble patch for continuous administration to acupuncture points and preparation method thereof

A continuous drug delivery and controllable technology, which is applied in the direction of drug devices and other medical devices, can solve unprecedented problems and achieve the effects of controllable quality, simple production process, and stable packaged drugs

Pending Publication Date: 2018-06-29
SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There is no report on acupoint administration, dose adjustment and continuous administration by means of patches, and there is no precedent for adjusting the transdermal absorption rate of drugs by setting a pressurized device.

Method used

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  • Controllable-pressure bubble patch for continuous administration to acupuncture points and preparation method thereof
  • Controllable-pressure bubble patch for continuous administration to acupuncture points and preparation method thereof
  • Controllable-pressure bubble patch for continuous administration to acupuncture points and preparation method thereof

Examples

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Embodiment Construction

[0060] see figure 1 , figure 2 as well as image 3 , the present invention firstly provides a kind of microbubble patch aiming at acupoint continuous administration, comprising gelatin microvesicle 1, sealing film 2, viscous film 3 and protective layer 4; gelatin microvesicle 1 is hollow bubble shape; The capsule 1 is provided with an opening, and one side of the sealing film 2 is hot-melt connected with the gelatin microvesicle 1 and closes the opening on the gelatin microvesicle 1; The corresponding window; the other side of the parafilm 2 is connected with the protective layer 4 through the adhesive film 3 . When using the microbubble patch for continuous drug administration at acupoints, first remove the protective layer to expose the viscous film. Be careful not to stretch the gelatin microbubble vesicle and the sealing film, and puncture the corresponding sealing film at the opening of the gelatin microbubble. A small hole is formed on the sealing film, and the micro...

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Abstract

The invention relates to a controllable-pressure bubble patch for continuous administration to acupuncture points and a preparation method thereof. The controllable-pressure bubble patch comprises gelatin bubbles, a sealing film, an adhesive film and a protective layer; the gelatin bubbles are hollow bubbles, openings of the gelatin bubbles are in hot melting with the sealing film, and the sealingfilm is connected with the protective layer through the adhesive layer. Besides, the gelatin bubbles are provided with pressurizing devices which run through the insides of the gelatin bubbles and supply pressure to the same. Each pressurizing device comprises a pressurizing pipe, a rubber piston arranged in the pressurizing pipe and a connecting rod connected with the rubber piston and driving the same to move in the pressurizing pipe freely, and the pressurizing pipe is communicated with the inside of the corresponding gelatin bubble. The pressure-controllable bubble patch is directly applied to an affected part or corresponding acupuncture point with adjustable dose and medicine permeation rate, quick action and good treatment effect, and has no anaphylactic reaction or irritative reaction to skin; the production process of the bubble patch is simple, environmentally friendly and realizes quality control.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and relates to a pressure-controllable microbubble patch for continuous drug administration at acupoints and a preparation method thereof. Background technique [0002] Administration through the skin is divided into local action on the skin (skin surface administration) and systemic action through skin penetration (transdermal absorption administration, transdermal administration). Transdermal drug delivery is a non-invasive drug delivery route that can maintain the effective drug level in the body, and can realize the controlled release of drugs with expected action time and long-term action time. Diffusion-controlled transdermal systems are devices designed to control the delivery of therapeutic ingredients from drug delivery devices to the skin or through the skin into the systemic circulation. Compared with traditional oral administration or injection administration, transdermal a...

Claims

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Application Information

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IPC IPC(8): A61M37/00
CPCA61M37/00A61M2037/0007Y02A50/30
Inventor 洪宗国宋庭宁肖新才
Owner SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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