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Light field microscope system, light field microscope and optical components thereof

A light field microscope and optical component technology, applied in the microscope field, can solve problems such as inability to optimize simultaneously, limited number of pixels, etc.

Active Publication Date: 2019-10-15
CENT FOR EXCELLENCE IN BRAIN SCI & INTELLIGENCE TECH CHINESE ACAD OF SCI
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Problems solved by technology

[0006] Second, due to the limitation of high image acquisition speed requirements or the limitation of acquisition camera process conditions, the axial resolution of the traditional light field microscope and the coverage of the three-dimensional visual field are mutually dependent on the limited number of pixels in the acquired image. Contradiction, cannot be optimized at the same time

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  • Light field microscope system, light field microscope and optical components thereof
  • Light field microscope system, light field microscope and optical components thereof
  • Light field microscope system, light field microscope and optical components thereof

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Embodiment Construction

[0027] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments. Note that the aspects described below in conjunction with the drawings and specific embodiments are only exemplary, and should not be construed as limiting the protection scope of the present invention.

[0028] figure 1 A schematic diagram of an optical assembly 100 of a conventional light field microscope is shown, and the optical system is proposed in a US patent (US 7,872,796B2) filed by TodorG.Georgiev in 2007. Such as figure 1 As shown, the optical assembly 100 includes a microscope objective lens 110 and a microlens array 120 . The microlens array 120 is composed of a plurality of microlenses, and the microlens array 120 is located at the back focal plane of the microscope objective lens 110 .

[0029] The object to be measured, such as the sample to be measured, is placed under the microscope objective lens 110, and each microlens of...

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Abstract

The invention provides an optical module used for an optical field microscope. The optical module comprises a microscopic objective and a microlens array arranged on a back focal plane of the microscopic objective, wherein the microlens array comprises a plurality of microlenses, the plurality microlenses are used for projecting real images of a sample under the microscope objective at different viewing angles onto a sensor located on an image plane of the optical field microscope, the plurality of microlenses are divided into at least two microlens groups, all the microlenses in each microlens group have the same optical parameters and axial positions, and the different microlens groups are configured to optically conjugate object planes under the microscope objective at different axial positions to the image plane on which the sensor is located.

Description

technical field [0001] The invention relates to microscope technology, in particular to a light field microscope system, a light field microscope and an optical assembly used for the light field microscope. Background technique [0002] Light field microscopy is an imaging technology that can obtain three-dimensional information of an object only by taking one camera exposure to collect data. The concept of using light field to obtain three-dimensional information of objects was proposed in the integral photography technology invented by Gabriel Lippmann in 1908. Its basic working principle is: the position and direction of propagation of light can be unique by measuring two non-coincident points in the space it passes through. Sure. Based on this concept, Marc Levoy first applied the concept of light field camera to fluorescence microscopy in 2006. [0003] The light field microscope proposed by Marc Levoy places a microlens array on the image plane of the microscope, and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G02B21/02G02B21/36
Inventor 王凯丛林杭苇
Owner CENT FOR EXCELLENCE IN BRAIN SCI & INTELLIGENCE TECH CHINESE ACAD OF SCI
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