Medical dressing with tissue inducing function for fading scars and preparation method of medical dressing

A technology to dilute scars and functions, applied in dressings, adhesive dressings, non-adhesive dressings, etc., can solve problems such as yellowing

Inactive Publication Date: 2018-08-14
SUZHOU NANOCRYSTAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It has similar biological stability and biocompatibility to aliphatic polycarbonate urethane, and the strength and solvent resistance of aromatic polyurethane, but the disadvantage is that it may produce mda and yellowing

Method used

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  • Medical dressing with tissue inducing function for fading scars and preparation method of medical dressing
  • Medical dressing with tissue inducing function for fading scars and preparation method of medical dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] A medical dressing for desalinating scars with tissue induction function for wounds with little exudate, the preparation method of which is as follows:

[0054] 1-) Dissolve degradable polyurethane in chloroform solution to make a 15% solution, and use electrospinning technology to spin a film with a pore size of 10-150 μm and a thickness of 0.1-0.2 mm, and evenly coat a layer of silicon Gel, which is a medical polyurethane diaphragm;

[0055] 1-2) Evenly coat the sodium hyaluronate gel on the medical polyurethane membrane obtained in step 1-1), and dry or air dry;

[0056] 1-3) Covering the adhesive backing layer on the film obtained in step 1-2), that is, forming the scar-reducing medical dressing of this embodiment with tissue induction function.

Embodiment 2

[0058] A medical dressing for desalinating scars with tissue induction function for wounds with little exudate, the preparation method of which is as follows:

[0059] 2-1) Dissolve degradable polyurethane in chloroform solution to make a 15% solution, PVP is made into a 15% solution with ethanol, use electrospinning technology to spray, and spin into a 1:1 weight ratio with a pore size of 10-150μm, 0.05-0.1mm thick film, evenly coated with a layer of polylysine PU (prepared into 1% hydrogel for later use), that is, medical polyurethane diaphragm;

[0060] 2-2) Covering the medical polyurethane membrane obtained in step 2-1) with an adhesive backing layer, that is, forming the scar-reducing medical dressing with tissue induction function of this embodiment.

Embodiment 3

[0062] A medical dressing for desalinating scars with a tissue-inducing function for wounds with a lot of exudate, the preparation method of which is as follows:

[0063] 3-1) Make PLGA (number average molecular weight 50,000, LA:GA=6:4) into a 15% chloroform solution, and use electrospinning technology to spin into a pore size of 100-300μm and a thickness of 0.2-0.3mm Membrane, evenly sprayed with silicone gel to form a medical polyurethane membrane;

[0064] 3-2) Make sodium alginate into a gel, evenly coat on the medical polyurethane diaphragm obtained in step 3-1), and dry or dry in the air;

[0065] 3-3) Select a suitable breathable membrane as the skin-adhesive backing layer for later use;

[0066] 3-4) The medical polyurethane membrane obtained in step (2) (3) is closely attached to the skin adhesive backing layer to form the scar-reducing medical dressing with tissue induction function of this embodiment.

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Abstract

The invention provides a medical dressing with a tissue inducing function for fading scars and a preparation method of the medical dressing. The medical dressing with the tissue inducing function forfading the scars contains a medical polyurethane film with porosity and thickness, a liquid absorbing layer and a back lining layer; the liquid absorbing layer and the back lining layer are sequentially laminated above the medical polyurethane film; medical polyurethane is a contact wound layer marking contact with the skin. According to the medical dressing provided by the invention, the medicalpolyurethane film with the tissue inducing function, certain porosity and the thickness is used as a cell migration stent layer for coating a wound; in the wound healing process, cells slowly migrateand grow by a film stent structure of the medical dressing disclosed by the invention; due to inconsistent degradation time of a degradable material, tissue absorption time is inconsistent, migrationand growth uniformity degree of the wound cells is inconsistent, and further a skin tissue-like structure is formed and generation of large scars is prevented.

Description

technical field [0001] The invention belongs to the field of medical dressings, and in particular relates to a scar-reducing medical dressing with tissue induction function. The liquid layer and the backing layer are successively stacked on the top of the polyurethane diaphragm, and the medical polyurethane is a contact wound layer in contact with the skin, wherein the medical polyurethane sheet-like structure has a pore size of 10-300 μm and a thickness of 0.01-0.5 mm. Background technique [0002] In real life, burns, traffic accidents, and mechanical injuries occur from time to time. Mild wounds can be healed with drugs or other means, but in slightly serious cases, the dermis is injured, and skin grafting may be involved. , In this way, whether it is in the skin grafting site, the skin extraction site, or the self-healing site, relatively obvious scars will appear. Although the disease is controlled, it leaves a relatively large psychological shadow. [0003] For a long...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/26A61L15/42A61L15/44A61L15/46A61F13/02
CPCA61F13/00017A61F13/00029A61F13/00063A61F13/0203A61L15/26A61L15/425A61L15/44A61L15/46A61L2300/216A61L2300/236A61L2300/404A61L2300/412C08L75/04
Inventor 不公告发明人
Owner SUZHOU NANOCRYSTAL PHARMA
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