Cosmetic composition and method
A composition and weight technology, applied in the direction of cosmetics, cosmetic preparations, cosmetic preparations, etc., can solve problems such as blemishes, greasy feeling, irritation, etc.
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Embodiment 1
[0082] A formulation with ingredients from Example 1 was prepared as a topical skin composition according to the present disclosure. The formulations in Tables 1 to 3 provide examples of cosmetic compositions according to the present disclosure.
[0083] Table 1^
[0084]
[0085]
[0086] ^The formulation can be prepared by mixing the ingredients in a beaker with heating at 70°C to 75°C until homogeneous. The formulation can then be cooled to constant room temperature (20°C to 25°C). In addition, additional ingredients may be added, if desired, for example to adjust the rheology of the composition or ingredients that provide benefits to the skin.
[0087] * Excipients may be added, for example, to adjust the rheology of the composition. Alternatively, the amount of water may vary so long as the amount of water in the composition is at least 60% by weight, preferably 60% to 85% by weight.
[0088] Table 2^
[0089] Element
% concentration (by weight) ...
Embodiment 2
[0097] (additional analysis)
[0098] Assays that can be used to determine the efficacy of any one of the ingredients disclosed throughout this specification and in the claims, or any combination of ingredients, or compositions having combinations of said ingredients, are known to those of ordinary skill in the art. method to determine. The following are non-limiting assays that can be used in the context of the present disclosure. It should be appreciated that other testing procedures may be used including, for example, objective and subjective procedures.
[0099] B16 Pigmentation Analysis: Melanogenesis is the process by which melanocytes produce melanin, the naturally occurring pigment that gives skin, hair, and eyes their color. Inhibiting melanogenesis is beneficial in preventing skin darkening and lightening dark spots associated with ageing. This bioassay uses the immortalized mouse melanoma cell line B16-F1 melanocytes (ATCC) to analyze the effect of compounds on m...
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