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Integrated plasma separating and hepatitis C virus immunity adsorbing device

A hepatitis C virus and plasma separation technology, applied in the field of medical devices, can solve the problems of increasing patient treatment costs, incomplete use of adsorbents, and inability to achieve adsorption, and achieves the reduction of treatment costs, blood volume, and consumables costs. Effect

Inactive Publication Date: 2018-09-28
WUHAN RUIFA MEDICAL DEVICES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing adsorbers cannot realize the cycle mode of "adsorption-regeneration-adsorption".
[0008] In addition, it should be pointed out that the adsorber disclosed in the patent with the publication number of CN 102631722 B is not divided into partitions, resulting in uneven adsorption of the fibrous adsorbent in the shell, resulting in unsatisfactory actual adsorption effect. Incomplete use of doses further increases patient treatment costs

Method used

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  • Integrated plasma separating and hepatitis C virus immunity adsorbing device
  • Integrated plasma separating and hepatitis C virus immunity adsorbing device
  • Integrated plasma separating and hepatitis C virus immunity adsorbing device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Such as figure 1 The one-piece plasma-separating hepatitis C virus immunoadsorber includes a housing 1, a blood inlet 2, a blood outlet 3, and a plasma outlet 4 that are arranged on the housing 1 and communicate with the interior thereof. There are a separation chamber 5 and an adsorption chamber 6; the two ends of the inner cavity of the housing 1 are provided with a sealing ring 7; the separation chamber 5 is provided with a hollow fiber membrane 8; the two ends of the hollow fiber membrane 8 are inserted and fixed to the sealing ring 7 and communicated The blood inlet 2 and the blood outlet 3; the separation chamber 5 and the adsorption chamber 6 communicate through the first porous membrane 9 that only allows blood plasma to pass through; the adsorption chamber 6 is provided with a hepatitis C virus immunosorbent 10; the adsorption chamber 6 Connected with plasma outlet 4. The casing 1 is also provided with a sample injection port 11 communicating with the adsorpti...

Embodiment 2

[0030] Such as Figure 2-4The one-piece immunoadsorber for separating hepatitis C virus from plasma shown in this embodiment has the same main features as that of Embodiment 1, and the difference is that the adsorption chamber 6 is also provided with a first adsorption chamber 14 and a first adsorption chamber 14. The second porous membrane 16 of the second adsorption chamber 15 that only allows the plasma in the blood to pass through, the second porous membrane 16 can allow the regeneration liquid 13 to pass through; Allowing plasma to permeate "means that only blood plasma is permeable in blood, and not only blood plasma is permeable in all substances (blood and others); the first adsorption chamber 14 communicates with the separation chamber 5 through the first porous membrane 9; The first adsorption cavity 14 is provided with a plurality of non-porous membranes 19 to separate it into a plurality of independent cavities 17, and each cavity 17 is provided with a wavy linear ...

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Abstract

The invention discloses an integrated plasma separating and hepatitis C virus immunity adsorbing device which comprises a shell and further comprises a blood inlet, a blood outlet and a plasma outletwhich are formed in the shell and communicate with the interior of the shell. A separating cavity and an adsorbing cavity are formed in an inner cavity of the shell. Sealing rings are arranged at thetwo ends of the inner cavity of the shell, and a hollow fiber film is arranged in the separating cavity. The two ends of the hollow fiber film are fixed to the sealing rings in an inserted mode and communicate with the blood inlet and the blood outlet. The separating cavity and the adsorbing cavity communicate through a first hole film only allowing plasma to penetrate through. A hepatitis C virusimmunity adsorbent is arranged in the adsorbing cavity. The integrated plasma separating and hepatitis C virus immunity adsorbing device has the beneficial effects that through forming of the separating cavity and the adsorbing cavity, plasma separating and plasma adsorbing can be synchronously conducted, and direct contact of blood corpuscles and the adsorbent is avoided, so that biocompatibility is improved; according to the illness situation of a patient, a regenerative treatment mode or a single-time adsorbing treatment mode can be automatically selected; and the consumable cost and the treatment cost are reduced, and the adsorbing effect is improved.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to an integrated immunoadsorber for separating hepatitis C virus from plasma. Background technique [0002] Hepatitis C virus immunosorbent is a filler of anti-hepatitis C virus antibody-carrier complex. Adsorption by Selective Binding of Human Hepatitis C Virus. Hepatitis C virus immunoadsorption therapy is a new technology developed in recent decades, mainly used for the treatment of hepatitis C. [0003] Compared with whole blood adsorption therapy, plasma adsorption therapy has less damage to blood cells and less impact on the internal environment of the human body, and has been widely used in the field of blood purification. The basic principle of plasma adsorption therapy is to introduce blood from the patient's body to the outside of the body, first separate the plasma from blood cells, and then specifically adsorb and remove the pathogenic substances in the plasma, so as to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/36
CPCA61M1/3679A61M2202/0057A61M2202/206
Inventor 张磊王业富胡定邦张媛温佳文何改粉韩玮
Owner WUHAN RUIFA MEDICAL DEVICES CO LTD
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