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A kind of pharmaceutical composition for treating tinea manus and pedis
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A composition and technology of tinea pedis, applied in drug combination, drug delivery, pharmaceutical formulation, etc., can solve problems such as easy recurrence, many adverse reactions, fungal drug resistance, etc., and achieve low treatment cost, painless treatment, and definite curative effect Effect
Inactive Publication Date: 2020-08-07
ANHUI UNIVERSITY
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Problems solved by technology
[0004] At present, miconazole nitrate, terbinafine, itraconazole, pevisone, fluconazole and other antifungal drugs are commonly used clinically in combination with glucocorticoids to treat tinea pedis. It will cause fungal drug resistance, and patients with poor liver and kidney function should not use it
In addition to chemical drugs, there are also many folk remedies circulating among the people, such as using garlic, potassium permanganate, vinegar, radish, pepper, alum, etc. to treat tinea manus, pedis, etc. Inhibits the fungus, but it is difficult to prevent its recurrence
[0005] In summary, it can be seen that there are still many deficiencies in the current therapeutic drugs for tinea manus and pedis, such as poor curative effect, difficult to cure and easy to relapse, serious adverse reactions, narrow application range, easy to produce drug resistance, long medication time, and expensive etc., the above deficiencies lead to poor compliance and tolerance of patients
Method used
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Embodiment 1
[0032] A pharmaceutical composition for the treatment of tinea manus and pedis, comprising the following raw material components in parts by weight:
[0034] Among them, the mixed enzyme is composed of 350 enzyme units of protease, 500 enzyme units of amylase, and 100 enzyme units of lipase;
[0035] Oregano extract is prepared through the following steps:
[0036] Remove impurities from the oregano medicinal material, wash, dry, and crush, add 5 times the volume concentration of 0.6% acetic acid aqueous solution, soak for 2 hours, filter, discard the filtrate, and add 10 times the volume of 75% ethanol to it after the filter residue is dried , soaked for 2 hours, then refluxed for 1 hour, filtered the medicinal liquid, and the filtrate was used for later use. Under the same conditions, the medicinal dregs were repeatedly extracted o...
Embodiment 2
[0038] A pharmaceutical composition for the treatment of tinea manus and pedis, comprising the following raw material components in parts by weight:
[0045] Among them, the mixed enzyme is composed of 350 enzyme units of protease, 500 enzyme units of amylase, and 100 enzyme units of lipase;
[0046] The preparation method of oregano extract is the same as in Example 1.
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Abstract
The invention relates to the field of external medicines, in particular to a pharmaceutical composition for treating tinea manus and pedis. The pharmaceutical composition of the present invention comprises specific weight parts of mixed enzyme, caprylic acid, oregano extract, lemongrass oil, garlic oil, salicylic acid and dimethyl sulfoxide, wherein the mixed enzyme is composed of protease, amylase and lipase composition. After testing, the pharmaceutical composition of the present invention has an ideal therapeutic effect on tinea pedis, and the composition of the present invention is an external pharmaceutical preparation, which has the advantages of convenient use, good safety, no pain in treatment, quick effect, definite curative effect, difficult recurrence after curing, It has the characteristics of wide application and low treatment cost.
Description
technical field [0001] The invention relates to the field of external medicines, in particular to a pharmaceutical composition for treating tinea manus and pedis. Background technique [0002] Tinea manum and pedis, collectively referred to as tinea manuum and tinea pedis, are skin diseases of the hands or feet caused by pathogenic fungal infections. They are the most common infectious diseases in dermatology. 70% of the disease is caused by Trichophyton rubrum , is highly contagious. Because the onset of this disease is affected by multiple factors such as infection, endocrine, autoimmunity, emotion, diet, etc., and the pathogenic mechanism is complicated, tinea manus and pedis have been considered as the most difficult to cure and most likely to relapse or reinfect among dermatophytosis. disease. [0003] The clinical manifestations of tinea manus and pedis are blisters, itching, erythema, papules, peeling, desquamation, or white and soft skin between the fingers, toes, ...
Claims
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Application Information
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