A kind of polysaccharide of rejuvenation grass with enhancing immune activity and its preparation method and application
A technology of rejuvenation grass and polysaccharides, which is applied in the field of immune-enhancing polysaccharides and its preparation and application, and can solve the problems that the research on the polysaccharide compounds of reincarnation has not yet been reported.
Active Publication Date: 2020-09-11
吉林益民堂制药有限公司 +1
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Problems solved by technology
At present, the research reports on the active components of Herba Reincarnation mainly focus on phenolic acids and flavonoids; the research on the polysaccharides of Herba Reincarnation has not been reported yet.
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[0020] The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention. If no specific technique or condition is indicated in the examples, it shall be carried out according to the technique or condition described in the literature in this field, or according to the product specification. The reagents or instruments used were not indicated by the manufacturer, and they were all conventional products that can be purchased through formal channels.
[0021] The present invention provides a method of extracting the polysaccharides from Herba Reincarnation, which is separated by macroporous resin D101, extracted with water and precipitated with alcohol, and G 50 Purification and other methods to prepare polysaccharides from Revenge of the Soul, characterized the physical and chemical properties and average structure of the polysaccharides, and studied that the polysaccharides can significantly promote the secreti...
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The invention relates to a senecionis cannabifolii herba polysaccharide with immuno-enhancement activity and a preparation method and an application thereof. The molecular weight of the senecionis cannabifolii herba polysaccharide is in the range of 4000-6500, and the senecionis cannabifolii herba polysaccharide is mainly composed of galacturonic acid, galactose and arabinose. The glucosidic bondconnecting mode is that a main chain is mainly connected by 1->3, 1->4 and 1->6; a branch is provided at the O-6 position of the 1->3 connection; the arabinose is at the non-reducing end. The senecionis cannabifolii herba polysaccharide is obtained from senecionis cannabifolii herba by aqueous extraction, macroporous adsorption, resin D101 separation, alcohol precipitation and Sephadex G50 purification. The senecionis cannabifolii herba polysaccharide has functions of enhancing immunity, anti-tumor effect and anti-inflammatory, and can be used for preparing medicine for treatment of chronic bronchitis and assisting treatment of pulmonary infection.
Description
technical field [0001] The invention relates to the polysaccharide obtained by extracting, separating and purifying the Herba Rejuvenatoria and its application in the preparation of auxiliary medicine for treating chronic bronchitis and pulmonary infection. Background technique [0002] Senecionis Cannabifolii Herba (SCH) is a characteristic resource in Northeast my country. Its medicinal material is the dried whole herb of Senecionis in the family Asteraceae. Single preparations using it as raw materials, such as Huihuncao Granules and Feining Oral Liquid, have been widely used in the treatment of chronic bronchitis, pulmonary infection and other diseases, and have a history of medicinal use for many years. In recent years, more than 20 pharmaceutical companies such as Jilin Xiuzheng, Huakang, Zixin, Yimin, Luobang, Tianjin Zhongxin, and Gerun have been using it to develop and produce new drugs, with considerable economic benefits and broad development prospects. At presen...
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IPC IPC(8): C08B37/00A61P37/04A61P35/00A61P29/00A61P11/00A61P31/00
CPCA61P11/00A61P29/00A61P31/00A61P35/00A61P37/04C08B37/0003
Inventor 金英纪圣君郭晶李艳茹周婷婷唐燕朱迪夫姜瑞芝
Owner 吉林益民堂制药有限公司