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Medicine composition for treating chronic obstructive pulmonary disease

A chronic obstructive and composition technology, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as adverse reactions and physical injuries, and achieve the effect of definite curative effect, improvement of symptoms, and high reliability

Pending Publication Date: 2018-11-16
北京东方运嘉科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these medicinal ingredients have a variety of adverse reactions after long-term use, causing great harm to the body.

Method used

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  • Medicine composition for treating chronic obstructive pulmonary disease
  • Medicine composition for treating chronic obstructive pulmonary disease
  • Medicine composition for treating chronic obstructive pulmonary disease

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0061] 2.3.2 Preparation of mouse tracheal secretions

[0062] 45 minutes after the last administration, 0.5 ml of phenol red was injected intraperitoneally, and 15 minutes later, the rats were killed by neck dislocation and the trachea was separated. Absorb 1.5ml NaHCO3, ultrasonically wash, then carefully lavage the inner wall of the trachea with a syringe, and centrifuge at 3000 rpm / 10min to obtain the mouse tracheal secretion.

[0063] 2.3.3 Drawing of standard curve and detection of phenol red excretion

[0064] (1) Configuration of standard products: dilute phenol red with physiological saline to 0, 10, 20, 40, 80, 120, 160 μg / ml for drawing a standard working curve.

[0065] (2) At 100 μl / well, add the standard substance and the sample to be tested into the 96-well plate in a certain order.

[0066] (3) Measure the absorbance at 546 nm with a microplate reader.

[0067] (4) Calculate the concentration: calculate the regression equation of the standard curve according...

Embodiment 1

[0095] Orange 300g, Scutellaria baicalensis 400g, Golden Buckwheat 400g, Baibu 250g, Perilla 200g, Seabuckthorn 200g, Aster 200g, Campanulaceae 200g

[0096] Take all the medicinal materials, add 8 times the amount of water, decoct and extract twice, combine the two extracts, concentrate and dry the extract under reduced pressure, and obtain 575 g of dry paste. According to conventional methods, granules are prepared.

Embodiment 2

[0098] Orange 400g, Scutellaria baicalensis 450g, Golden buckwheat 450g, Baibu 200g, perilla seed 225g, seabuckthorn 175g, aster 250g, bellflower 150g

[0099] Take all the medicinal materials, add 6 times the amount of water, decoct and extract 3 times, combine the extracts from the 3 times, concentrate and dry the extracts under reduced pressure, and obtain 615 g of dry paste. According to conventional methods, granules are prepared.

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Abstract

The invention relates to a medicine composition for treating chronic obstructive pulmonary disease and a preparation method, wherein the composition consists of dry tangerine peel, fructus perillae, fagopyrum dibotrys, scutellaria baicalensis, radix stemonae, sea-buckthorns, radix asteris and platycodon grandiflorum. The composition has definite treatment effect of resolving the chronic obstructive pulmonary disease, especially having excellent effect on patients, suffered from the obstructive pulmonary disease, with excessive phlegm. A preparation method of the composition is also provided.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, more specifically, to a pharmaceutical composition for treating chronic obstructive pulmonary disease and a preparation method thereof. Background technique [0002] Chronic obstructive pulmonary disease (COPD), also known as COPD, is a common chronic disease characterized by airflow limitation that is not fully reversible. The incidence rate of people over 40 years old is as high as 9% in the world. The incidence rate of 8.2%. The main manifestations of COPD are repeated cough, expectoration, shortness of breath, and decreased activity tolerance, which can further develop into pulmonary hypertension, pulmonary heart disease, and respiratory failure, with high morbidity and mortality. COPD is currently the eighth leading cause of death in the world, and is expected to become the third leading cause of death and fifth in economic burden in the world by 2020. [0003] The ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P11/00
CPCA61K36/904A61P11/00A61K36/185A61K36/28A61K36/346A61K36/535A61K36/539A61K36/70A61K36/752A61K2236/51A61K2236/39A61K2236/331A61K2300/00
Inventor 晁恩祥晁燕曾风英王小花王宏图
Owner 北京东方运嘉科技发展有限公司
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