Nanoparticle tracking device
A nanoparticle and tracking device technology, which is applied in the field of measurement, can solve the problems of difficult calibration process, difficult to provide standard size nanoparticle solution, and impracticability, so as to achieve the effect of improving accuracy
Active Publication Date: 2018-11-20
北京世纪朝阳科技发展有限公司
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Problems solved by technology
[0017] However, it is difficult to provide a standard size nanoparticle solution with the required refractive index and particle size with a standard concentration, making the calibration process not only difficult, but sometimes even impossible
Therefore, it is difficult to implement an inaccurate calibration process for the measurement results caused by the uneven light intensity of the laser beam irradiating the sample cell, and it is difficult to obtain accurate nanoparticle measurement results
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[0045] Various exemplary embodiments, features, and aspects of the present disclosure will be described in detail below with reference to the accompanying drawings. The same reference numbers in the figures indicate functionally identical or similar elements. While various aspects of the embodiments are shown in drawings, the drawings are not necessarily drawn to scale unless specifically indicated.
[0046] The word "exemplary" is used exclusively herein to mean "serving as an example, embodiment, or illustration." Any embodiment described herein as "exemplary" is not necessarily to be construed as superior or better than other embodiments.
[0047] In addition, in order to better illustrate the present disclosure, numerous specific details are given in the following specific implementation manners. It will be understood by those skilled in the art that the present disclosure may be practiced without some of the specific details. In some instances, methods, means, componen...
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The disclosure relates to a nanoparticle tracking device, comprising: a laser for emitting a first laser beam; an optical shaping unit for shaping the first laser beam into a laser beam having uniformlight intensity, the optical shaping unit comprising a scanning unit for adjusting the direction of the first laser beam to obtain a second laser beam and reflecting the second laser beam to a concentrating unit, and the concentrating unit for concentrating the second laser beam into a third laser beam and emitting the third laser beam to a sample cell; an image acquisition unit for acquiring animage of nanoparticles in the sample cell; and an image processing unit connected with the image acquisition unit for analyzing the image to obtain parameters of a sample in the sample cell. The optical shaping unit is arranged on the emergent light path of the laser and can shape the laser beam emitted by the laser into a laser beam having uniform light intensity, thereby improving the accuracy of nanoparticle measurement and reducing the complexity of the calibration process.
Description
technical field [0001] The present disclosure relates to the field of measurement technology, in particular to a nanoparticle tracking device. Background technique [0002] The commonly used techniques for analyzing the size distribution of nanoparticles are: static light scattering, dynamic light scattering, electron microscopy, flow cytometry and nanoparticle tracking. [0003] Nanoparticle tracking technology is based on the Brownian motion of particles, and the degree of Brownian motion (diffusion coefficient) of particles is related to factors such as temperature, viscosity, and particle size. [0004] Nanoparticle tracking technology directly tracks the movement of each particle, and calculates the particle size of each particle by analyzing the relative displacement of each particle. By counting the particle sizes of a large number of particles, the particle size distribution of the particles is obtained. [0005] Such as figure 1 As shown, the laser light emitted ...
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IPC IPC(8): G01N15/02
CPCG01N15/0211
Inventor 张达王继军江学舟
Owner 北京世纪朝阳科技发展有限公司