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Smashing device used for domperidone bulk drugs

A pulverizing device and domperidone technology are applied in the field of pulverizing devices for domperidone raw materials, which can solve the problems of low pulverization efficiency and difficult to control pulverization quality, and achieve the effects of improving pulverizing efficiency, increasing collision frequency, and increasing pulverization rate.

Inactive Publication Date: 2018-11-30
江苏又一城智能科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A crushing device is needed in the production and processing of domperidone API, the crushing efficiency of the existing crushing device is low, and the crushing quality is difficult to control

Method used

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  • Smashing device used for domperidone bulk drugs

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Embodiment Construction

[0015] The present invention will be further explained below in conjunction with the accompanying drawings and specific embodiments. It should be understood that the following specific embodiments are only used to illustrate the present invention and are not intended to limit the scope of the present invention.

[0016] As shown in the figure, a crushing device for domperidone bulk drug includes a crushing body 1, the crushing body 1 is a barrel-shaped structure with an upper end opening, and the upper end of the crushing body 1 is provided with a top cover 2 matching it, The upper part of the inner cavity of the crushing main body 1 is provided with a rotating cylinder 3, and the lower part of the inner cavity is filled with a second steel ball 4. The rotating cylinder 3 has a cylindrical structure, and the rotating cylinder 3 is rotatably supported in the crushing main body 1 through a bearing 5. , the lower end of the rotating cylinder 3 is provided with a filter screen plat...

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Abstract

The invention provides a smashing device used for domperidone bulk drugs. The device comprises a smashing body, a top cover is arranged at the top end of the smashing body, a rotation cylinder is arranged on the upper portion of an inner cavity, second steel balls are contained in the lower portion of the inner cavity, the lower end of the rotating cylinder is provided with a filter net plate, first steel balls are contained in the rotating cylinder, a lower rotating shaft is arranged below the filter net plate, a lower stirring paddle set is distributed on the lower segment of the lower rotating shaft, an upper rotating shaft is arranged below the top cover, and an upper stirring paddle set is distributed on the lower segment of the upper rotating shaft. The device has the beneficial effects that upper stirring paddles can stir the first steel balls in the rotating cylinder, the collision frequency of the first steel balls and the bulk drugs can be improved, the primary and rapid smashing is achieved, in addition, the rotating cylinder and the upper stirring paddles are controlled to be opposite in the rotating direction, the stirring rate of the upper stirring paddles for the first steel balls is improved, the smashing rate of the first steel balls for the bulk drugs is improved, the lower stirring paddles stir the second steel balls, secondary smashing of the bulk drugs is achieved, the smashing efficiency is effectively improved, and the smashing quality is ensured.

Description

technical field [0001] The invention relates to the technical field of pulverizing devices, in particular to a pulverizing device for domperidone bulk drug. Background technique [0002] The Chinese alias of domperidone is: 5-chloro-1-[1-[3-(2-oxo-1-benzimidazole) propyl] 4-piperidinyl]benzimidazol-2-one; domperidone Ketone; 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1, 3-Dihydro-2H-benzimidazol-2-one; Propiperidone; Properidone; Chlorperidone; Domperidone; Pyrazole; Doperidone. When producing and processing domperidone bulk drug, a pulverizing device is needed. The pulverizing efficiency of the existing pulverizing device is low, and the pulverizing quality is difficult to control. Contents of the invention [0003] In order to solve the above problems, the present invention discloses a crushing device for domperidone raw material drug, which effectively improves the crushing efficiency and ensures the crushing quality. [0004] In...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B02C17/16B02C17/10B02C23/16B02C17/18
CPCB02C17/163B02C17/10B02C17/18B02C23/16
Inventor 李晓东姚译敏
Owner 江苏又一城智能科技有限公司
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