Absolute flow rate measuring device and method for Doppler optical coherence tomography
A technology of Doppler optics and flow velocity measurement, which is applied in the field of absolute flow velocity measurement devices of Doppler optical coherence tomography, can solve problems such as cumbersome process, complex mathematical operations, and inability to reconstruct three-dimensional structures, so as to improve practicability, experiment Accurate results and strong operability
Active Publication Date: 2018-12-18
CENT SOUTH UNIV
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The disadvantage of this method is that the three-dimensional structure cannot be reconstructed if the outer wall structure of the sample is not clear, and the construction of a mathematical model requires complex mathematical operations, and the process is cumbersome
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[0034] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.
[0035] In order to make the above objectives, features and advantages of the present invention more obvious and understandable, the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.
[0036] The invention provides an absolute flow velocity measuring device for Doppler optical coherence tomography. The device uses the DOCT system to find the state where the long...
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The invention discloses an absolute flow rate measuring device for Doppler optical coherence tomography. The method comprises a short coherence light source, a circulator, an optical coupler, a reference arm system, a sample arm system, a spectrometer, and a computer; the short coherence light source is used for emitting short coherence laser, the circulator is arranged on an outgoing optical pathof the short coherence light source, the optical coupler is arranged on an outgoing optical path of the circulator, the optical coupler is configured to split the short coherence laser transmitted via the circulator into two beams, the reference arm system is used to reflect first laser to obtain reference reflected light, the sample arm system is used for reflecting second laser to obtain samplereflected light, the reference reflected light and sample reflected light enter the spectrometer; the spectrometer is used for detecting interference spectrums of the reference reflected light and the sample reflected light; the sample arm system is also used to measure a Doppler angle of a sample being measured, and the computer is used for calculating an absolute flow rate based on the interference spectrums and the Doppler angle. The device can be used for rapidly and accurately calculating the absolute flow rate.
Description
Technical field [0001] The invention relates to the field of absolute flow rate measurement, in particular to an absolute flow rate measurement device and method of Doppler optical coherence tomography. Background technique [0002] Puller optical coherence tomography (DOCT) has a wide range of applications, such as blood flow measurement in fundus blood vessels to diagnose early diabetes, blood flow measurement in brain vessels of small animals to study the hemodynamics of cerebrovascular diseases and early embryos Academic measurement. The flow velocity directly calculated by DOCT is actually the projection velocity, that is, the projection value of the particle velocity in the sample in the direction of incident light. The projection value changes with the Puller angle, so the projection speed has defects in practical applications. To get the absolute flow velocity, you need to get the Doppler angle. The basic principle of the existing Doppler angle measurement method is to...
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IPC IPC(8): A61B5/00A61B5/026
CPCA61B5/0033A61B5/0066A61B5/0073A61B5/0075A61B5/0261A61B5/7235A61B5/7257
Inventor 马博妍
Owner CENT SOUTH UNIV