Antibacterial glove for hemodialysis care and preparation method thereof

A hemodialysis and glove technology, applied in gloves, applications, protective clothing, etc., can solve the problems of poor antibacterial and anti-infection performance, insufficient tear resistance, allergic reactions, etc. The effect of good practicability and easy availability of raw materials

Active Publication Date: 2019-02-15
江西中红普林医疗制品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to overcome the defects in the prior art, the present invention aims to provide a biocompatibility, excellent mechanical properties, wear resistance, anti-aging, antistatic, antibacterial and anti-infection properties, good anticoagulant and antithrombotic properties, Use safe and reliable antibacterial gloves for hemodialysis care to effectively solve the more ...

Method used

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  • Antibacterial glove for hemodialysis care and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0029] A preparation method of antibacterial gloves for hemodialysis care, comprising the steps of:

[0030] Ⅰ Preparation of polythiadioic acid 1,2-diamino-5-trifluoromethylbenzimidazole amide: Add 1kg of thiadioic acid and 1.22kg of 1,2-diamino-5-trifluoromethylbenzimidazole Add 0.4 kg of dicyclohexylcarbodiimide, 0.3 kg of 4-dimethylaminopyridine and 0.1 kg of tetrabutylammonium bromide to 10 kg of dimethyl sulfoxide, and stir and react at 90 ° C for 2 hours under a nitrogen atmosphere , then stirred and reacted at 125°C for 8 hours. After the reaction, it was precipitated in water, washed with ethanol for 3 times, and then dried to a constant weight at 80°C in a vacuum oven to obtain polythiadioic acid 1, 2-Diamino-5-trifluoromethyl benzimidazolamide;

[0031] II Glove molding: Grind 0.5kg of chlorosulfonated polyethylene into powder in a ball mill, and then add 1kg of polythiadioic acid 1,2-diamino-5-trifluoromethylbenzimidazole amide prepared through step I , and then ...

Embodiment 2

[0036] A preparation method of antibacterial gloves for hemodialysis care, comprising the steps of:

[0037] Ⅰ Preparation of polythiadioic acid 1,2-diamino-5-trifluoromethylbenzimidazole amide: Add 1kg of thiadioic acid and 1.22kg of 1,2-diamino-5-trifluoromethylbenzimidazole Add 0.45kg of dicyclohexylcarbodiimide, 0.3kg of 4-dimethylaminopyridine and 0.1kg of tetrabutylammonium bromide to 11kg of N,N-dimethylformamide, Stir the reaction at 95°C for 2.3 hours, and then stir the reaction at 127°C for 8.5 hours. After the reaction, it precipitates in water, washes the precipitated product with ethanol for 4 times, and then places it in a vacuum drying oven at 83°C to dry to constant weight. Polythiadioic acid 1,2-diamino-5-trifluoromethylbenzimidazole amide;

[0038] II Glove molding: Grind 0.5kg of chlorosulfonated polyethylene into powder in a ball mill, and then add polythiadioic acid 1,2-diamino-5-trifluoromethylbenzimidazole amide 1.1 kg, then the mixture is added to the...

Embodiment 3

[0043] A preparation method of antibacterial gloves for hemodialysis care, comprising the steps of:

[0044] Ⅰ Preparation of polythiadioic acid 1,2-diamino-5-trifluoromethylbenzimidazole amide: Add 1kg of thiadioic acid and 1.22kg of 1,2-diamino-5-trifluoromethylbenzimidazole Add 0.5kg of dicyclohexylcarbodiimide, 0.3kg of 4-dimethylaminopyridine and 0.1kg of tetrabutylammonium bromide to 13kg of N-methylpyrrolidone, and stir the reaction at 100°C under a neon atmosphere 2.5 hours, then stirred and reacted at 130°C for 9 hours. After the reaction, it was precipitated in water, washed with ethanol for 4 times, and then dried in a vacuum oven at 85°C to constant weight to obtain polythiadiic acid 1,2-Diamino-5-trifluoromethyl benzimidazolamide;

[0045] II Glove molding: Grind 0.5 kg of chlorosulfonated polyethylene into powder in a ball mill, and then add polythiadioic acid 1,2-diamino-5-trifluoromethylbenzimidazole amide 1.3 prepared through step I kg, and then the mixture ...

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Abstract

The invention discloses a preparation method of an antibacterial glove for hemodialysis care. The preparation method comprises the following steps of (1) preparation of polythiazide 1,2- diamido-5-trifluoromethyl benzimidazolamide, (2) glove forming, and (3) ion exchange. The invention further discloses the antibacterial glove for the hemodialysis care obtained according to the preparation methodof the antibacterial glove for the hemodialysis care. The antibacterial glove for the hemodialysis care has the advantages that the biocompatibility is good, the mechanical performance, abrasion resistance, ageing resistance, anti-static electricity and antibacterial property and infectious prevention are excellent, anticoagulation and antithrombosis are excellent, and the use is safe and reliable.

Description

technical field [0001] The invention relates to the technical field of medical equipment, in particular to an antibacterial glove for hemodialysis care and a preparation method thereof. Background technique [0002] With the progress of the times and the development of science and technology, hemodialysis technology has become more and more mature. Clinically, hemodialysis has become one of the main ways of renal replacement therapy for patients with acute and chronic renal failure. It drains the blood from the body to the outside of the body, through a dialyzer composed of countless hollow fibers, the blood and the electrolyte solution (dialysate) with a similar concentration to the body are inside and outside the hollow fiber, using the function of the semi-permeable membrane to pass through diffusion / convection Carry out material exchange, remove metabolic waste in the body, maintain electrolyte and acid-base balance; at the same time remove excess water in the body, thus...

Claims

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Application Information

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IPC IPC(8): A41D19/015C08G69/26C08G69/28C08J7/14C08L77/06C08L23/34
CPCA41D19/0055A41D2500/52C08G69/26C08G69/28C08J7/14C08J2377/06C08J2423/34
Inventor 邓生卫刘艺
Owner 江西中红普林医疗制品有限公司
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