Hydrogen peroxide sterilization verification method

Abstract

The invention discloses a hydrogen peroxide sterilization verification method. The hydrogen peroxide sterilization verification method comprises the following steps: acquiring an airflow stream pattern blind spot and / or a temperature uniformity blind spot in a to-be-tested object; CI blind spot testing: starting hydrogen peroxide sterilization on the to-be-tested object, and acquiring a CI blind spot, wherein CI is a chemical indicator; BI blind spot test: arranging BI at the positions of the CI blind spot and the airflow stream pattern blind spot and / or the temperature uniformity blind spot which are obtained in the steps in the to-be-tested object, wherein the BI is a biological indicator; after setting a set of hydrogen peroxide sterilization parameters, starting hydrogen peroxide sterilization, after sterilization is completed, judging whether fatality rate of BI reaches a set threshold value or not, and if the fatality rate of BI reaches the set threshold value, then completing sterilization verification of the set of hydrogen peroxide sterilization parameters; and if the fatality rate of BI does not reach the set threshold value, correcting the hydrogen peroxide sterilizationparameter, and restarting hydrogen peroxide sterilization until the set threshold value is reached. The hydrogen peroxide sterilization verification method has the advantages of simplicity in principle, simplicity and convenience in operation, capability of achieving the optimal hydrogen peroxide sterilization effects and the like.

Description

technical field [0001] The invention mainly relates to the technical field of sterilization, in particular to a hydrogen peroxide sterilization verification method mainly applicable to the field of food, medicine and other packaging equipment. Background technique [0002] The method of hydrogen peroxide steam sterilization has been applied to the sterilization of various spaces, especially in the field of packaging equipment such as food and medicine, such as isolators is one of them. The 2015 edition of the "Chinese Pharmacopoeia" in the third part of the sterilization method mentions the gas hydrogen peroxide sterilization method, but there is no literature or information on the development of the sterilization process or the sterilization blind spot test. Details. [0003] In traditional equipment, when loading components for hydrogen peroxide sterilization, it is necessary to set the parameters of hydrogen peroxide sterilization through program development, so as to en...

AI Technical Summary

Problems solved by technology

The 2015 edition of the "Chinese Pharmacopoeia" in the third part of the sterilization method mentions the gas hydrogen peroxide sterilization method, but there is no literature or information on the development of the sterilization process or the sterilization blind spot test. detailed introduction

However, the existing operating parameters for hydrogen peroxide sterilization are often set manually based on empirical values, lack of verification methods, and there is no set of reasonable verification methods to finally obtain the best control parameters

In the absence of optimum control parameters, over or under hydrogen peroxide sterilization can result

For example, if the time of passing hydrogen peroxide is too long, it will continuously cause waste and increase the cost, and it will also cause corrosion or damage to various components of the entire equipment, affecting the compatibility between each sensor and other actuators, seriously affecting to the entire life of the device

Or, if the time of passing hydrogen peroxide is too short, the sterilization effect will be reduced

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