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Paste containing heparin-like composition

A composition and heparin technology, applied in the direction of drug combination, non-active ingredients of polymer compounds, anti-inflammatory agents, etc., can solve the problems of imperfect application of heparin-like compositions, achieve inhibition of smooth muscle cell proliferation, cure edema and edema, Broad-spectrum antibacterial effect

Inactive Publication Date: 2019-03-22
沈阳亿欣源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the prior art, the application of the heparinoid composition on the skin, mucous membrane and other action sites is not perfect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1: A paste containing heparinoid composition, including 40 parts of heparinoid, 59 parts of matrix material (the matrix material is glycerin gelatin, water), 0.1 part of vitamin C, 0.18 part of preservative, collagen 0.5 servings.

Embodiment 2

[0020] Example 2: A paste containing heparinoid composition, including 20 parts of heparinoid, 67.8 parts of matrix material (the matrix material is glycerin gelatin, water), 0.125 parts of vitamin C, 2 parts of preservative, collagen 10 servings.

Embodiment 3

[0021] Example 3: A paste containing heparinoid composition, including 10 parts of heparinoid, 74.6 parts of matrix material (the matrix material is glycerin gelatin, water), 0.2 parts of vitamin C, 5 parts of preservative, collagen 20 servings.

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PUM

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Abstract

The invention discloses a paste containing a heparin-like composition, and belongs to the field of biotechnology. The paste containing the heparin-like composition is characterized by comprising 0.01-80 parts of mucopolysaccharide, 0.01-90 parts of a matrix material, 0.01-5 parts of an antioxidant, 0.01-5 parts of a preservative and 0.01-20 parts of a moisturizing agent. Under a synergistic actionof a keratin softening agent and the natural moisturizing agent, the paste containing the heparin-like composition can inhibit the excessive growth of collagen fiber and reduce scar formation; the paste containing the heparin-like composition can retain moisture on the surface of skin to soften the collagen fiber and enhance the elasticity and has an effect of softening a hypertrophic scar.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a paste containing a heparin-like composition used in medicines, medical equipment, cosmetics, disinfection products and the like. Background technique [0002] Heparinoid is a mucopolysaccharide. In 1948, when Jorpes and Gardell prepared heparin from liver and lung, they obtained a polysaccharide composed of D-glucuronic acid and D-glucosamine. These substances are similar in structure to heparin , but the degree of sulfation is low, and the anticoagulant activity is low, but after more sulfation, its properties change greatly. By combining with the surface of vascular endothelium, it promotes the release of endogenous amino polysaccharides with antithrombotic activity, which can improve local microcirculation, increase blood flow and blood flow velocity, thereby improving intermediate metabolism, promoting skin nutrition supply and waste excretion , play a role in redu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K47/42A61K31/726A61K31/727A61K31/737A61P29/00A61P31/04A61P31/10A61P31/12A61P7/10A61P17/02
CPCA61K9/0014A61K9/06A61K31/726A61K31/727A61K31/737A61K47/42A61P7/10A61P17/02A61P29/00A61P31/04A61P31/10A61P31/12
Inventor 唐财坤关成云李丹胡莹满国荣朱凯月肖秀梅马立强
Owner 沈阳亿欣源生物科技有限公司
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