Liquid-based thin-layer cell sheet production clamp

A thin-layer cell and liquid-based technology, applied in the field of vertical slide clips, can solve the problem of cell collection on unfavorable glass slides

Active Publication Date: 2019-03-26
YONGKANG JIUJIU TECH
View PDF7 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When the cell slicer is centrifuged, the water in the liquid-based cells in the settling tube is separated from the cells due to centrifugation. At this time, the cells are adsorbed on the glass slide, and then the water is poured out through the settling tube. The cells adsorbed on the glass slide will also flow out with the water during the process, which is not conducive to the collection of cells on the slide

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Liquid-based thin-layer cell sheet production clamp
  • Liquid-based thin-layer cell sheet production clamp
  • Liquid-based thin-layer cell sheet production clamp

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: A kind of liquid-based thin-layer cell slide clip, such as figure 1 with image 3 As shown, it includes a fixed seat 1 and a settling tube 11 vertically arranged on the fixed seat 1, the bottom of the settling tube 11 communicates with the fixed seat 1, and an annular groove 117 is provided at the lower end of the settling tube 11, and an annular groove 117 is provided on the groove wall. There is an inclined surface 1171 extending from the lower end of the settling tube 11 to the direction away from the axis of the settling tube 11, and a sealing rubber ring 116 is fixed in the ring groove 117, so that when the film-making clamp is in a centrifugal state, the cell and the water channel are restricted outside the settling tube 11; Offer slot 112 respectively on seat 1 two side walls (as figure 2 As shown), the slot 112 is slidingly connected with a slide 111, and the slide 111 is provided with a placement groove 1111 for the settling tube 11 to embed on th...

Embodiment 2

[0036] Embodiment 2: a kind of liquid-based thin-layer cell slide clip, the difference from embodiment 1 is that, as Figure 5 As shown, a filter cup 118 is sleeved in the settling tube 11, a limit block 1184 is provided on the outer wall of the filter cup 118, and a limit groove 11841 for the limit block 1184 to slide in is provided on the settling tube 11 inner wall, and the limit The cooperation of the block 1184 and the limit groove 11841 limits the rotation of the filter cup 118 in the settling tube 11; the opening of the filter cup 118 is provided with an outwardly extending support plate 1181, and the support plate 1181 limits the filter cup 118 along the settling tube 11 Move down; the bottom of the filter cup 118 is provided with a through hole 1182 at the position directly above the cell sedimentation area 114, and a filter membrane 11821 for closing the through hole 1182 is provided on the wall of the through hole 1182, and the filter membrane 11821 is set to filter ...

Embodiment 3

[0037] Embodiment 3: A kind of liquid-based thin-layer cell slide clip, the difference from Embodiment 1 is that, as Figure 6 As shown, slide grooves 1191 parallel to the slots 112 are respectively provided on the two side walls of the fixing seat 1, and a pressing plate 119 that is slidingly connected with the sliding groove 1191 is provided at the lower end of the glass slide, and a pressing plate 119 is provided on the pressing plate 119 to connect upwardly. Squeeze the pressing block 1192 of the glass slide so that the lower end of the slide 111 and the settling tube 11 are closely attached to ensure that the liquid-based cells on the slide 111 are always in the settling tube 11 when the slide is clamped in a centrifugal state. Inside.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a liquid-based thin-layer cell sheet production clamp, belongs to a vertical sheet production clamp for a centrifugal liquid-based thin-layer cell sheet production machine andaims at providing the liquid-based thin-layer cell sheet production clamp capable of reducing outflow of cells on a glass slide with water and furthermore ensuring that the cells on the glass slide are collected. A technical scheme of the liquid-based thin-layer cell sheet production clamp has the key points that a baffle is arranged between inner walls of lower ends of sedimentation tubes; the lower end of the baffle is in contact with the glass slide; the baffle is arranged to be close to the center position of the sheet production machine, and the length of the baffle is smaller than the diameter of the sedimentation tube; a space formed by the sedimentation tube and the glass slide is divided into a cell sedimentation region and a water absorption region by the baffle; the cell sedimentation region is arranged to be close to the center position of the sheet production machine; the upper end of the baffle is provided with a moving plate located on the same plane with the baffle; oneend of the moving plate is hinged with the inner wall of the sedimentation tube, and the other end of the moving plate is in contact with the inner wall of the sedimentation tube; the moving plate isprovided with a tension spring above the cell sedimentation region; and the inner wall, located in the water absorption region, of the sedimentation tube is provided with water absorption cotton.

Description

technical field [0001] The invention relates to a vertical film-making clip for a centrifugal liquid-based thin-layer cell film maker, in particular to a liquid-based thin-layer cell film-making clip. Background technique [0002] In medicine, the observation of cell smears can be used to screen and diagnose female cervical cancer and other diseases. The screening of exfoliated cells includes the following steps: use a sampler to collect specimens, store in preservation solution, oscillate and mix, base fluid thin layer of cells Film preparation and microscope observation. One of the important steps is the production of liquid-based thin-layer cells, that is, transferring useful cells to glass slides to make cell smears with clear background, neat and uniform cells, and single-layer tiling for inspection and research by researchers. However, the exfoliated cells sampled during film production often contain impurities such as mucus and red blood cells, resulting in an unclea...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/28
CPCG01N1/2813
Inventor 胡学静
Owner YONGKANG JIUJIU TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap