Small animal pain-measuring device and application thereof

Abstract

The invention discloses a small animal pain-measuring device and an application thereof, wherein the device comprises a separating test platform, a lower rotating device and a liftable bracket. The separating test platform comprises an animal buffer zone, an animal mechanical pain measuring zone and an animal thermal radiation pain measuring zone from inside to outside, and the animal mechanical pain measuring zone and the animal thermal radiation pain measuring zone have multiple compartments. An extractable third partition plate is arranged between the animal buffer zone and the animal mechanical pain measuring zone, and an extractable fourth partition plate is arranged between the animal mechanical pain measuring zone and the animal thermal radiation pain measuring zone. The device canbe rise and fall up and down to the required height during pain measuring in different methods during experimental animal pain measuring, can rotate 360 DEG, is fixed at a position where a tester needs fixed observation, and is easy to operate; two pain measuring modes can be convenient to switch randomly in a condition without affecting the adaptability of animals to the environment; a platform is convenient to clean up in time to ensure the smooth progress of pain measurement; data are guaranteed to be real and reliable, and the operation of the tester is facilitated.

Description

technical field [0001] The invention relates to the field of basic medical scientific research, in particular to a small animal pain measuring device and its application. Background technique [0002] Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage that is subjective. "Pain threshold" refers to the lowest stimulus value that causes pain. In the research of the basic mechanism of pain, the detection of pain threshold is usually used to measure the body's sensitivity to pain. Pain research in experimental animals mainly focuses on the determination of two pain thresholds: one is the temperature pain threshold, and the main detection device is a radiant heat pain meter, which uses a certain intensity of infrared or visible beams to irradiate the plantar skin of rodents , to measure the time from the start of irradiation to the animal’s foot-lifting and avoiding action due to pain, which is called the Thermal Withdrawal L...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the above-mentioned problems existing in the prior art, and provide a small animal pain measuring device and its application. Surface cleanup issues and interference issues during testing

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