A Simple Mechanical Pain Stimulator Applicable to Small Animal Magnetic Resonance Imaging Instrument

Abstract

The invention provides a simple mechanical pain stimulation device applicable to a small animal nuclear magnetic resonance imager, comprising a first syringe, further comprising a piston cylinder, wherein a piston is arranged in the piston cylinder, one end of the piston cylinder communicates with a communicating mouth part of the piston cylinder, and the other end of the piston cylinder is an open end; a piston snap ring is disposed on an inner wall, close to the open end, of the piston cylinder; a tip end member is disposed at a side, facing the open end of the piston cylinder, of the pistoncylinder; and the mouth part of the first syringe communicates with the piston cylinder through a hose. The simple mechanical pain stimulation device of the invention can be used in conjunction witha timer for achieving controllability of stimulation time. The simple mechanical pain stimulation device has a plurality of advantages such as easy production, stable stimulation intensity, and compatibility with MRI equipment.

Description

technical field [0001] The invention relates to the field of animal experiment devices, and more particularly relates to a simple mechanical pain stimulation device suitable for small animal nuclear magnetic resonance imaging apparatus. It is suitable for giving small animals mechanical pain at a certain part, a certain intensity, and a certain duration during the MRI process, which can be controlled remotely, and can realize the immediate administration and removal of pain stimulation. Background technique [0002] An MRI machine is a non-invasive, ionizing radiation-free tissue imaging device. Due to the high resolving power of MRI, especially soft tissue, its structural imaging function has been widely used in clinical detection. In addition, the NMR functional imaging instrument also has the function of functional imaging. The so-called functional imaging refers to the change of brain activity reflected by the change of image signal value. Functional MRI is commonly u...

AI Technical Summary

Problems solved by technology

However, in the functional imaging experiment of the small animal MRI, the mechanical pain stimulus cannot be directly applied by the tester because the cavity part of the small animal imager is too small

However, due to the strong magnetic field of nuclear magnetic resonance instruments, most mechanical and electronic devices cannot be used.

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