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Quality control method and equipment for traditional Chinese medicine decoction piece processing

A quality control method and the technology of Chinese herbal pieces, which are applied in the direction of making medicines into special physical or taking forms, using material absorption weighing, measuring devices, etc., can solve the problem of accurately determining the content of index components of Chinese herbal pieces, etc. problem, to achieve the effect of realizing quick judgment, ensuring consistency and stability

Active Publication Date: 2019-04-19
ANHUI CHINA RESOURCES JINCHAN PHARMA CO LTD
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is: in order to solve the technical problem that it is difficult to accurately determine the index component content of the sample of Chinese herbal decoction pieces by the existing online detection equipment and method for processing herbal decoction pieces, and provide a quality control method and equipment for the processing of herbal decoction pieces

Method used

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  • Quality control method and equipment for traditional Chinese medicine decoction piece processing
  • Quality control method and equipment for traditional Chinese medicine decoction piece processing
  • Quality control method and equipment for traditional Chinese medicine decoction piece processing

Examples

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Embodiment 1

[0030] This embodiment provides a kind of equipment for processing Chinese herbal decoction pieces, such as figure 1 As shown, it includes a processing tank 1 and a circulation pipeline 2. The circulation pipeline 2 is arranged outside the processing tank 1 and communicates with the upper and lower ends of the processing tank 1. The processing tank 1 is connected with a hopper 11 and a liquid outlet. The circulation pipeline 2 is provided with a detection tank 4 and a circulation pump 3 connected with the circulation pipeline 2 from top to bottom, and the circulation pump 3 is connected with the bottom of the processing tank 1 through the first liquid outlet valve 18 to detect A detection probe 5 is installed in the pool 4, and the detection probe 5 communicates with the spectrum analyzer 6. The spectrum analyzer 6 stores component detection models of the processed solutions of various Chinese medicinal materials, and the spectral information of the processed solutions in the d...

Embodiment 2

[0037] This embodiment provides a quality control method for processing traditional Chinese medicine decoction pieces using the equipment of Embodiment 1. Taking the processing of Aconitum aconitum as an example: Aconitum aconitum is the dried mother root of the plant Aconitum ranunculaceae, which is highly toxic, and the main toxic substance is diester Aconitine (C 34 h 47 NO 11 ), Hypoaconitine (C 33 h 45 NO 10 ) and neoaconitine (C 33 h 45 NO 11 )) total content T c Not more than 0.040%, that is, not more than 400μg / g, the hydrolysis product of diester-type alkaloids-benzoylaconitine (C 32 h 45 NO 10 ), benzoyl aconitine (C 31 h 43 NO 9 ) and benzoyl neoaconitine (C 31 h 43 NO 10 ) of the total content T b It should be 0.070% to 0.15%; the specific quality control method is as follows:

[0038] 1. Take the manually selected clean Aconitum aconitum, and detect the content of the toxic substance diester alkaloids in it. Based on the dried Aconitum aconitum, ...

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Abstract

The invention relates to a quality control method and equipment for traditional Chinese medicine decoction piece processing, and belongs to the technical field of traditional Chinese medicine decoction piece processing. The equipment comprises a processing tank and a circulating pipeline which is arranged outside the processing tank and connected with the upper end and the lower end of the processing tank, a feeding hopper and a liquid outlet pipe are connected to the processing tank, a circulating pump and a detection pool which are communicated are installed on a circulating pipeline, the circulating pump is communicated with the processing tank through a first liquid outlet valve, a detection probe is installed in the detection pool, and the detection probe is in communication connection with an optical spectrum analyser. The quality control method for traditional Chinese medicine decoction piece processing comprises the steps that traditional Chinese medicinal materials are added into the processing tank for processing traditional Chinese medicine decoction pieces, water is added, heating is conducted, and processing is conducted; when the processing temperature reaches a process setting value, the content of toxic substances in a processing solution and the content of hydrolysis products are detected online; when the processing conditions are met, processing is finished, the content of index components in the processing solution can be accurately detected online, and fast judgment of a processing end point is achieved.

Description

technical field [0001] The invention relates to a quality control method and equipment for processing Chinese herbal decoction pieces, and belongs to the technical field of Chinese herbal decoction pieces processing. Background technique [0002] The processing of traditional Chinese medicine decoction pieces is a pharmaceutical technology adopted according to the needs of syndrome differentiation and treatment, the nature of the drug itself, and the different requirements of dispensing and preparations. Scientific processing can reduce toxicity and increase efficiency, while unscientific processing will often cause the active ingredients of medicinal materials to be lost. It even increases the toxicity and side effects. For example, some Chinese medicinal materials such as Aconitum Aconitum, Aconitum Aconitum, Aconite, Pinellia, and Polygonum multiflorum contain first-class toxicity. If the processing process of these traditional Chinese medicines is unreasonable, or the qua...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J3/00G01D21/02G01N5/02G01N21/3577G01N21/359G01N30/02G01N30/06G01N30/14G01N30/34G01N30/74
CPCG01D21/02G01N5/025G01N21/3577G01N21/359G01N30/02G01N30/06G01N30/14G01N30/34G01N30/74A61J3/00
Inventor 高波罗川
Owner ANHUI CHINA RESOURCES JINCHAN PHARMA CO LTD
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