Magnetic resonance double-pulse brain white matter micro-measurement system and method

A measurement system and measurement method technology, applied in diagnostic recording/measurement, medical science, sensors, etc., can solve the problem of not being able to obtain the radius, direction, and distribution of brain white matter

Inactive Publication Date: 2019-05-24
周文瑾 +2
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  • Application Information

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Problems solved by technology

Diffusion tensor imaging can only obtain some average diffusion rate, which is studied to the extent of anisotropy, but cannot obtain microscopic indicators such as the radius, direction, and distribution of white matter.

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  • Magnetic resonance double-pulse brain white matter micro-measurement system and method
  • Magnetic resonance double-pulse brain white matter micro-measurement system and method
  • Magnetic resonance double-pulse brain white matter micro-measurement system and method

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Embodiment Construction

[0040] The magnetic resonance double-pulse white matter microscopic measurement system and method of this patent application will be described in detail below with reference to the accompanying drawings and embodiments.

[0041] This technology consists of a hardware system and a software system. The hardware system includes a Siemens 3T-MRI magnetic resonance instrument, which comes with a set of software package IDEA Package (Interactive Development Environment for Applications), which includes a research agreement signed with Siemens Compiled new double-PGSE sequence software. The software system consists of three modules: data preprocessing (removing Rician noise), parameter global fitting (including geometric model, mathematical model, gamma statistics, global fitting) and visualization. The program is written by the mathematical software Matlab and can run on Windows or Linux systems.

[0042] figure 1 It is a structural block diagram of the MRI double-pulse brain whi...

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Abstract

The invention discloses a magnetic resonance double-pulse brain white matter micro-measurement system which comprises a magnetic resonance imaging instrument hardware system and a signal processing software system connected with the magnetic resonance imaging instrument hardware system. The magnetic resonance imaging instrument hardware system is used for generating parameter-adjustable double pulse and outputting a plurality of measurement signal values of all positions of brain white matters. The signal processing software system is used for preprocessing the measurement signal values, removing Rician noise, globally fitting the signal values without the Rician noise, calculating the radiuses, the directions and distribution of the brain white matters and displaying visual results. The magnetic resonance double-pulse brain white matter micro-measurement system can measure micro-indexes such as the radiuses, the directions and distribution of the brain white matters, and a tool is provided for deepening fundamental brain research into micro-level.

Description

【Technical field】 [0001] This patent application generally relates to the technical fields of medical equipment, medical image processing and neuroimaging, and more specifically relates to a magnetic resonance double-pulse white matter microscopic measurement system and a magnetic resonance double-pulse white matter microscopic measurement method, which can be used non-invasively The radius, direction and distribution of white matter were determined by microscopic observation. 【Background technique】 [0002] Artificial intelligence and the treatment of brain diseases will be the two areas most affected by advances in brain research. At present, countries all over the world have invested heavily in brain project research. China's "Brain Project" focuses on social needs, with "brain health" as the theme of the plan. The main research should focus on the working principle of the brain and the frontier fields related to major brain diseases, with particular emphasis on juvenil...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055
Inventor 周文瑾周林祥吴晓东
Owner 周文瑾
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