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Local biochemistry molecular layer decorating method for micro-sensor part

A micro sensor and molecular layer technology, which is applied in the fields of semiconductor, biochemistry and engineering, can solve the problems of large measurement errors, achieve the effect of reducing modification costs, high-throughput real-time detection, and realizing micro-modification and large-scale local modification

Pending Publication Date: 2019-05-31
TIANJIN POLYTECHNIC UNIV
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AI Technical Summary

Problems solved by technology

This discovery has a huge impact on the research of eliminating the large detection error caused by the adsorption of a large number of biochemical molecules and the imprecise modification
[0004] So far, breakthroughs have been made in the research of biochemical sensors at home and abroad, but there are still many technical problems, such as: when biochemical sensors modify biochemical molecules in a large area, the measurement error will be large due to large area adsorption

Method used

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  • Local biochemistry molecular layer decorating method for micro-sensor part
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Embodiment Construction

[0045] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be described in further detail below in conjunction with specific embodiments and with reference to the accompanying drawings.

[0046] The present invention provides a method for locally modifying biochemical molecular layers for micro sensor devices, by adopting a micro-inkjet printing device with a piezoelectric micro-spray head 4, an XY displacement stage 2, and a two-dimensional or three-dimensional workbench 6 to realize the biochemical molecular layer local modification.

[0047] Such as figure 1 as shown, figure 1 It is a structural schematic diagram of a micro-inkjet printing device for a method of locally modifying a biochemical molecular layer for a micro-sensing device according to an embodiment of the present invention. It mainly includes: piezoelectric micro-spray head 4, used to print modified biochemical molecules; air pressure co...

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Abstract

The invention discloses a local biochemistry molecular layer decorating method for a micro-sensor part. The method is characterized in that a micro ink spraying method is used for printing same or different biochemistry molecules to a specific area, local area biochemistry functionalized decorating is carried out on the surface of the sensor part, and thus the sensor part can meet the requirementof biochemistry detection. A device for the local biochemistry molecular layer decorating method comprises a piezoelectric micro spraying head, two cameras, an XY moving table, a closed container, a closed container pneumatic control unit, an XY moving table data collecting and controlling system, a micro spraying head control unit and an environment control and measurement unit, wherein the sizeof printing drops of the piezoelectric micro spraying head can be controlled through voltage, the two cameras are used for observing the position of the micro spraying head and a device in a three-dimensional manner, the device is arranged on the XY moving table and can move in the horizontal plane along with the XY moving table, the closed container is used for containing printed biochemistry molecules, the closed container pneumatic control unit is used for adjusting the size of gas pressure in the closed container, the XY moving table data collecting and controlling system can precisely control the moving displacement of the moving table in the XY direction, the micro spraying head control unit is used for adjusting and controlling the size, the number and the state of the printing drops, and the environment control and measurement unit is used for measuring the surrounding environment condition. According to the local biochemistry molecule decorating method carried out through themicro ink spraying device, high-sensitivity, high-stability and high-throughput real-time detection to biochemistry molecules to be detected can be achieved effectively.

Description

technical field [0001] The invention belongs to the fields of semiconductor, biochemistry and engineering, and in particular relates to a method for locally modifying a biochemical molecular layer of a micro sensor device. Background technique [0002] With the continuous expansion of the application of biochemical sensors in the fields of food, medicine, environment and process monitoring [1-2], higher requirements are put forward for the performance of biochemical sensors: high sensitivity, high stability, low cost and so on. In addition, in response to the application requirements in the fields of disease diagnosis, food detection, and environmental monitoring, the development of biochemical sensors presents the following trends: Multi-function: through the use of interference, three-dimensional high-speed three-dimensional inkjet [3], self-assembly and other technologies to develop multi-functional sensors, Arrange as many sensors as possible in the smallest possible are...

Claims

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Application Information

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IPC IPC(8): B29C64/112B29C64/20B29C64/393B33Y10/00B33Y30/00B33Y50/02
Inventor 王晶晶张丽岳金明刘宏伟陈力颖张赞允
Owner TIANJIN POLYTECHNIC UNIV
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