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A kind of essential oil sustained-release antibacterial capsule with bagasse as wall material and preparation method thereof

A technology for essential oils and bagasse, which is applied in the directions of antibacterial drugs, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., can solve the problems of low encapsulation rate of essential oils in capsules, difficult to combine essential oils uniformly, etc., and achieves alleviation Environmental pressure, improve the encapsulation rate, improve the effect of slow release effect

Active Publication Date: 2021-04-23
GUANGXI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Using bagasse as wall material to prepare essential oil capsules can make full use of bagasse, but because bagasse has less pore structure and a relatively flat structure, it is difficult for essential oils to be evenly combined in the pores, and the embedding rate of essential oil in capsules is likely to be low.

Method used

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  • A kind of essential oil sustained-release antibacterial capsule with bagasse as wall material and preparation method thereof

Examples

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Effect test

Embodiment 1

[0034] An essential oil slow-release antibacterial capsule with bagasse as the wall material is prepared by co-precipitation method with bagasse as the wall material and plant essential oil as the core material; the core-to-wall ratio (mass ratio) is 1:5.

[0035] The preparation method comprises the following steps:

[0036] S1. Preparation of bagasse solution

[0037] The bagasse is crushed, sieved, cleaned, and dried for later use; then the treated bagasse is carbonized in a vacuum environment, and the temperature is raised from room temperature to 600°C at 60°C / min; after carbonization at 600°C for 1 hour, cool to room temperature Sugarcane charcoal was prepared; finally, the sugarcane charcoal was mixed with water and stirred in a water bath at 60° C. for 2 hours to make a bagasse solution. The mass concentration of bagasse solution is 5%.

[0038] S2. Preparation of essential oil ethanol solution

[0039] According to the volume ratio of plant essential oil to ethanol...

Embodiment 2

[0045] An essential oil slow-release antibacterial capsule with bagasse as the wall material, prepared by co-precipitation method with bagasse as the wall material and plant essential oil as the core material; the core-to-wall ratio is 1:1.

[0046] The preparation method comprises the following steps:

[0047] S1. Preparation of bagasse solution

[0048] The bagasse is crushed, sieved, cleaned, and dried for later use; then the treated bagasse is carbonized in a vacuum environment, and the temperature is raised from room temperature to 550°C at 60°C / min; after carbonization at 550°C for 1 hour, cool to room temperature Sugarcane charcoal was prepared; finally, the sugarcane charcoal was mixed with water and stirred in a water bath at 50° C. for 3 hours to make a bagasse solution. The mass concentration of bagasse solution is 2%.

[0049] S2. Preparation of essential oil ethanol solution

[0050]According to the volume ratio of plant essential oil and ethanol as 1:10, the p...

Embodiment 3

[0056] An essential oil slow-release antibacterial capsule with bagasse as the wall material, prepared by co-precipitation method with bagasse as the wall material and plant essential oil as the core material; the core-to-wall ratio is 1:10.

[0057] The preparation method comprises the following steps:

[0058] S1. Preparation of bagasse solution

[0059] The bagasse is crushed, sieved, cleaned, and dried for later use; then the treated bagasse is carbonized in a vacuum environment, and the temperature is raised from room temperature to 650°C at 60°C / min; after carbonization at 650°C for 1 hour, cool to room temperature Sugarcane charcoal was prepared; finally, the sugarcane charcoal was mixed with water and stirred in a 70°C water bath for 1.5h to make a bagasse solution. The mass concentration of bagasse solution is 10%.

[0060] S2. Preparation of essential oil ethanol solution

[0061] According to the volume ratio of plant essential oil and ethanol as 1:30, the plant ...

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Abstract

The invention provides an essential oil sustained-release antibacterial capsule with bagasse as a wall material and a preparation method thereof, belonging to the technical field of food manufacturing. Bagasse is used as the wall material, plant essential oil is used as the core material, and it is prepared by co-precipitation method; the core-to-wall ratio is 1:1-10, and then the prepared capsules are added to the chitosan solution, then TPP solution, and centrifuged The essential oil sustained-release antibacterial capsule is obtained; the mass concentration of the chitosan solution is 0.2-0.5%, and the mass concentration of the TPP solution is 0.2-0.5%. The sustained-release antibacterial capsule is prepared by using bagasse as the wall material and plant essential oil as the core material, which fully exerts the antibacterial effect of the plant essential oil, and fully utilizes the bagasse to utilize waste, thereby reducing waste of resources and alleviating environmental pressure.

Description

technical field [0001] The invention relates to the technical field of capsule preparation, in particular to an essential oil sustained-release antibacterial capsule with bagasse as a wall material and a preparation method thereof. Background technique [0002] Essential oils are volatile and aromatic substances extracted from natural plants. Traditional Chinese medicine essential oil is a special essential oil with medicinal properties, which has been widely used in medicine, daily chemical production, food industry and other fields. Proven by long-term pharmacology and clinical studies, Chinese medicine essential oils have various pharmacological activities, such as: anti-oxidation, anti-inflammation, antibacterial, bactericidal, antiviral or insecticidal effects. But it is easy to volatilize at normal temperature, and easy to oxidize and deteriorate, which affects its application effect. [0003] Microencapsulation technology is a protective technology that uses film-fo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/62A61K9/54A61K47/46A61K47/36A61K36/53A61K36/61A61K36/54A61K36/752A61K36/534A61K36/282A61P31/04A61K31/722
Inventor 陆登俊蔡晨晨梁欣泉马瑞佳
Owner GUANGXI UNIV
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