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Drug for preventing or treating oral diseases

A technology for oral diseases and drugs, which is applied in the field of drugs in the field of medical technology, can solve the problems of patients' daily life inconvenience, inability to eat normally, large dosage of medication, etc., and achieve the effect of eliminating redness, swelling, heat, pain, repair, and convenient medication

Inactive Publication Date: 2019-06-21
陕西军兴生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The clinical symptoms of this type of disease are local swelling, bleeding, pain, tissue atrophy, etc. In severe cases, the oral cavity is ulcerated and cannot eat normally, which brings inconvenience to the daily life of the patient.
[0005] Oral disease is one of the common diseases that endanger human health. At present, most of the drug treatments are systemic and local drugs. Only a small dose maintains complete drug activity, and the concentration of the drug reaching the local area is very low

Method used

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  • Drug for preventing or treating oral diseases
  • Drug for preventing or treating oral diseases
  • Drug for preventing or treating oral diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The present embodiment provides a kind of medicine for the prevention or treatment of oral diseases, which is formulated by the following component dosages:

[0031]

[0032]

[0033] The preparation method of the medicine is:

[0034] 1) Get dog ridge hair, wash and dry and pass through a 100-mesh sieve for subsequent use;

[0035] 2) get clove oil, calcium hydroxide, iodoform, peruvian balsam and lidocaine and mix, and stir at room temperature to obtain a mixed solution;

[0036] The dog spine hair obtained in step 1) is immersed in the mixed solution of step 2), so that it is completely soaked to obtain the final product.

[0037] The dog ridge hair in this embodiment has a barrier function to prevent double infection and avoid the occurrence of alveolar inflammation after tooth extraction. Due to the sticky fibers contained in it, it is easy to stick to the bottom of the socket after being placed in the socket. After the wound has healed, it is gradually de...

Embodiment 2

[0039] The present embodiment provides a kind of medicine for the prevention or treatment of oral diseases, which is formulated by the following component dosages:

[0040]

[0041] The preparation method of the medicine is:

[0042] 1) Get gelatin sponge, pulverize and pass through a 100-mesh sieve for subsequent use;

[0043]2) get clove oil, calcium hydroxide, iodoform, peruvian balsam and tetracaine and mix, and stir at room temperature to obtain a mixed solution;

[0044] Immerse the gelatin sponge powder obtained in step 1) into the mixed solution of step 2) to completely infiltrate it, that is, it is obtained.

[0045] The gelatin sponge in this embodiment is a protein sponge with hemostatic function that can be absorbed and implanted. It has good biocompatibility and degradability, and can promote the release of thromboplastin after the destruction of platelets and promote blood clot coagulation. , thereby facilitating hemostasis. The gelatin sponge can combine w...

Embodiment 3

[0047] The present embodiment provides a kind of medicine for the prevention or treatment of oral diseases, which is formulated by the following component dosages:

[0048]

[0049] The preparation method of the medicine is:

[0050] 1) Take chitosan, pulverize and pass through a 100-mesh sieve for later use;

[0051] 2) get clove oil, calcium hydroxide, iodoform, peruvian balsam and loxoprofen and mix, and stir at room temperature to obtain a mixed solution;

[0052] 3) Immerse the chitosan obtained in step 1) into the mixed solution of step 2) to make it completely infiltrated.

[0053] The chitosan in this example has good degradability, cell adhesion and biocompatibility, and is non-immunogenic and non-toxic, and is a good drug carrier. Studies have found that chitosan has pharmacological effects such as anti-inflammatory, hemostasis, and promoting tissue healing, and the adhesion time on the oral mucosa can reach more than 4 days.

[0054] The medicine for the preve...

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Abstract

The invention discloses a drug for preventing or treating oral diseases. According to the drug, gelatin sponge, rhizoma cibotii or chitosan serves as a carrier, clove oil, iodoform, calcium hydroxideand Peru balsam serve as active ingredients, and an appropriate amount of local anesthetics are added, wherein the local anesthetics are one of lidocaine, tetracaine and loxoprofen. The drug has various pharmacological effects such as anti-inflammation, pain relief, disinfection, antisepsis, hemostasis, promotion of tissue regeneration, prevention of secondary infections, and promotion of periodontal tissue regeneration. Moreover, the drug is convenient to take and easy to remove and has high permeability; the pain of patient's oral lesions can be quickly relieved, external liquid is effectively prevented from entering cavities, the barrier function of the drug can prevent double infections, the temperatures of the lesions are reduced, and dysfunctions such as local swelling and pain of mucous membranes are quickly eliminated, so that the drug is beneficial to repair of the oral mucous membranes.

Description

technical field [0001] The invention belongs to medicines in the field of medical technology, in particular to a medicine for preventing or treating oral diseases. Background technique [0002] Oral hygiene is an integral part of healthy life and an important symbol of the progress of social civilization. As the concept of oral health is transformed into the concept of social life, the attention to oral health is increasing, and the prevention and treatment of oral diseases are becoming more and more important. The oral cavity is a complex and complete ecosystem, an important channel for food to enter the digestive tract, and a place for the secretion of some digestive juices. The suitable temperature, humidity and food residues in the oral cavity provide a favorable environment and conditions for the growth and reproduction of microorganisms. It is the best environment for microorganisms to live and breed, which can lead to the occurrence of various diseases. Under normal...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61K47/42A61K47/46A61K47/36A61K9/00A61P1/02A61P29/00A61K8/92A61K8/9789A61K8/19A61K8/20A61K8/65A61K8/9749A61K8/73A61Q11/00A61Q17/00A61L15/44A61L15/40A61L15/42A61L15/46A61L15/20A61L15/28A61L15/32A61L15/18A61K33/18A61K33/08A61K31/167A61K31/245A61K31/192
Inventor 王晓娟贺建军李振斌郑炳真
Owner 陕西军兴生物医药科技有限公司
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