Generalized predictive control insulin infusion amount calculating method based on adaptive reference curve strategy

A generalized predictive control and reference curve technology, applied in adaptive control, flow control, pressure infusion, etc., can solve problems such as difficult to achieve control effect
CN109925569AInactive Publication Date: 2019-06-25GUANGDONG FOOD & DRUG VOCATIONAL COLLEGE +2
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
GUANGDONG FOOD & DRUG VOCATIONAL COLLEGE
Publication Date
2019-06-25
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a generalized predictive control insulin infusion amount calculating method based on an adaptive reference curve strategy. The method includes utilizing real-time monitored human blood glucose data to predict future blood glucose change by using a CARIMA model, and then adopting the minimum variance to control and track the adaptive reference curve and calculate the infusion rate of an insulin pump in real time. The infusion is performed to reduce the blood glucose fluctuation of the human body and control the blood glucose in a predetermined target interval. Compared with the existing generalized predictive control algorithm, the adaptive reference curve strategy adopted can generate the reference curve suitable for different patients according to the blood glucosefluctuations of the patients to achieve control of the infusion rate of the insulin pump.
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Description

technical field

[0001] The present invention relates to the field of insulin pump infusion volume estimation, and more specifically, relates to a generalized predictive control insulin infusion volume calculation method based on an adaptive reference curve strategy. Background technique

[0002] The existing insulin infusion control algorithm includes proportional calculus control algorithm, fuzzy control algorithm and model control algorithm and so on.

[0003] Proportional Integral Derivative (PID) control is a relatively mature and widely used industrial control algorithm. The design of the insulin pump based on the PID algorithm has been realized by the Steil team of Medtronic MiniMed. Its main design idea is: the three components of the PID algorithm, the proportional, differential and integral components, respectively simulate the physiological transmission process of insulin secreted by human β cells. Among them, the linear proportional component corresponds to the i...

Claims

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