Method for producing porous hydrogel sheet and porous hydrogel sheet produced by the same

Abstract

The present invention relates to a manufacturing method of a porous hydrogel sheet and a hydrogel sheet manufactured by the manufacturing method. The manufacturing method of the porous hydrogel sheet comprises the following steps: (1) manufacturing A gelling agent, a gelling accelerator, and a solvent for a hydrogel sheet composition solution; (2) coating the hydrogel sheet composition solution into a sheet form; (3) applying the composition solution to the sheet A hydrogel sheet coated with a material form is gelled with a composition solution to produce a hydrogel sheet; (4) pre-freezing the hydrogel sheet; and (5) pre-freezing the pre-freezing The hydrogel sheets were freeze-dried. The method for producing a hydrogel sheet according to the present invention can provide a porous hydrogel sheet capable of ensuring quantification and stability of active ingredients and having an improved liquid absorption.

Description

Manufacturing method of porous hydrogel sheet and porous hydrogel manufactured by the manufacturing method film technical field [0001] The present invention relates to a method for producing a porous hydrogel sheet and a porous hydrogel sheet produced by the method, In more detail, the production includes the steps of pre-freezing and freeze-drying the hydrogel sheet so that the liquid absorption is improved. A method for a highly porous hydrogel sheet and a porous hydrogel sheet produced by the production method. Background technique [0002] A hydrogel is a network of hydrophilic polymer chains with water as the dispersion medium. the hydraulic Glue is insoluble in water, expands and can contain a lot of water in the structure, showing softness very similar to natural tissue. [0003] The hydrogel is used in the field of medicine due to its unique hydrophilicity and softness, such as tissue engineering, cell Cell culture, Sustained‑release drug delivery system, bi...

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Problems solved by technology

[0005] However, in the case of the hydrogel produced by Patent Document 1, since the hydrogel itself has a high moisture content, when a functional ingredient is applied to the hydrogel, the concentration of the active ingredient is diluted, and after Efficiency of transdermal drug delivery may be reduced

In addition, the moisture contained in the hydrogel may cause the risk of spoilage due to the proliferation of microorganisms, which may negatively affect the stability of the active ingredient during the effective period of the product.

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