Splicing-type allograft bone plug for cranial defect repairing and preparation method of splicing-type allograft bone plug

Abstract

The embodiment of the invention discloses a splicing-type allograft bone plug for cranial defect repairing. The bone plug comprises a plug cap and a plug pin which are made from allogeneic cortical bones and a plug body made from allogeneic cancellous bones, the plug cap is provided with an arc curved surface, and a dovetail groove protrusion is arranged at the other end, opposite to the arc curved surface, of the plug cap; a cylinder hole used for sleeving the plug pin is formed in the center of the plug cap, and the plug body sleeves the other end of the plug pin and is provided with a dovetail groove notch matched with the dovetail groove protrusion; the invention further discloses a preparation method of the splicing-type allograft bone plug for cranial defect repairing. The whole boneplug is made from the allogeneic cortical bones, has the same components, structure and mechanical properties as those of the human bone, is excellent in biocompatibility, provides convenience for filling for conventional skull drill holes in surgical operations and is specially suitable for filling repairing for skull defects of children.

Description

technical field [0001] The embodiments of the present invention relate to the technical field of biomedicine, in particular to a spliced ​​allogeneic bone plug for skull defect repair and a preparation method thereof. Background technique [0002] Skull defect is a very common clinical disease, common in traffic accident injuries, gunshot wounds, skull malignant tumors, decompressive craniectomy and other trauma and postoperative. Reconstructing a complete skull can protect brain tissue and reduce complications. It can also maintain the shape of the head and face and restore the appearance of the patient; [0003] At present, the clinically commonly used skull repair materials mainly include non-metallic materials such as polymethyl methacrylate and hydroxyapatite, and metal materials such as titanium alloy implants and titanium mesh, which have good biocompatibility and high mechanical strength. , can effectively resist secondary trauma and protect the brain, but it has th...

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Problems solved by technology

[0004] Titanium alloy materials are difficult to degrade, and permanent space occupation leads to abnormal growth of new bone. Due to the heat conduction effect of titanium metal, patients receiving titanium metal implants often feel uncomfortable in hot weather, resulting in low biocompatibility and poor clinical effect. , and the bone plug inserted into the patient's skull defect is formed in one piece. The one-piece production method not only wastes metal materials, but also makes the preparation process cumbersome, which is not conducive to the medical staff's rapid preparation for surgery.

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