A method for preparing ellagic acid by gallnut, the prepared ellagic acid and its application

Abstract

The invention discloses a method for preparing ellagic acid by using Rhus chinensis Mill., the prepared ellagic acid and application of ellagic acid. The method comprise the following steps: (1), mixing Rhus chinensis Mill. powder with deionized water at room temperature, performing stirring for 1-3 hours, performing filtration, and taking the supernatant; and (2), taking the obtained supernatant,adding sodium persulfate and sodium hydrogencarbonate sequentially, adjusting the pH value to 8-9, performing still standing for 10-20 hours at room temperature, then adjusting the pH value to 3-6 byusing inorganic acid, performing solid-liquid separation, and collecting the solid which is the ellagic acid, wherein the addition amount of sodium persulfate is 5-10% of the mass of the Rhus chinensis Mill., and the mass ratio of the added sodium persulfate to sodium hydrogencarbonate is 3:2. Water and Rhus chinensis Mill. are mixed firstly so as to extract tannic acid, the ellagic acid is obtained through oxidation, alkalization and acidification, and all the operation can be carried out at normal temperature and normal pressure; and the reaction conditions are mild, the operation is simple, the obtained product has high purity and good yield, and the method has good application prospects.

Description

technical field [0001] The invention relates to the technical field of organic synthesis, in particular to a method for preparing ellagic acid by using gallnuts, the prepared ellagic acid and an application thereof. Background technique [0002] The scientific name of gallnut (Rhus chinensis Mill.), also known as Baichongcang, Baiyaojian, and Gallia, is a female horned aphid or aphid of the family Aphididae of the order Homoptera that parasitizes the plant "Saltwood" and its The young leaves or petioles of other plants of the same genus are stabbed to form a cystic aggregate of galls, which is obtained after roasting and drying. In addition, Galla is also a kind of medicinal material, which can treat many diseases. The main production areas of Chinese Gallnut are concentrated in Qinling Mountains, Daba Mountains, Wudang Mountains, Wushan Mountains, Wuling Mountains, Emei Mountains, Dalou Mountains, Daliang Mountains and other mountainous and hilly areas. The vertical distr...

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Problems solved by technology

(2) High Performance Liquid Chromatography (HPLC) (especially Reverse Phase-High Performance Liquid Chromatography (RP-HPLC)) is currently the most common method for determining the content of ellagic acid method, the method is simple to operate, requires less sample volume, short measurement time, accurate experimental results and good reproducibility, but the required instruments are relatively expensive

However, in the prior art, the process of preparing ellagic acid from Galla galla is relatively complicated, which makes its industrial production cost relatively high, and it is necessary to further improve it.

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