Metabonomics-based traditional Chinese medicine four-property discrimination method

Abstract

The invention discloses a metabonomics-based traditional Chinese medicine four-property discrimination method, and belongs to the field of traditional Chinese medicine theory modernization research. The method comprises the following steps: S1, data acquisition; S2, establishment of an extraction variable template; S3, data preprocessing; S4, construction of a drug property discrimination model. According to the metabonomics-based traditional Chinese medicine four-property discrimination method disclosed by the invention, a metabolite group is the reaction of the physiological and pathologicalstate of the body, and the method is based on metabonomics data and conforms to the traditional basic thought of judging drug properties by drug effects; meanwhile, the method combines a mode recognition technology to construct a drug property discrimination model and judge the four properties of unknown drugs and foods, thereby avoiding the subjectivity of a traditional drug property discrimination method, enabling the result to be objective, and enabling the judgment to be more accurate. The invention achieves the innovation of a traditional Chinese medicine property discrimination method.

Description

technical field [0001] The invention relates to the research field of modernization of traditional Chinese medicine theory, and more particularly, to a method for discriminating the four qi of traditional Chinese medicine based on metabolomics. Background technique [0002] The "four qi" of traditional Chinese medicine are cold, hot, warm and cool, also known as the four properties of traditional Chinese medicine, which are an important part of the theory of traditional Chinese medicine properties. Its normative standards are of great significance. Its research results can not only provide theoretical guidance for clinical drug use and experimental research, but also play an extremely important role in promoting the development and utilization of new resources of traditional Chinese medicine, maintaining the characteristics and advantages of traditional Chinese medicine, improving the clinical efficacy of traditional Chinese medicine, and modernizing traditional Chinese medi...

AI Technical Summary

Problems solved by technology

Studying the four-qi theory of traditional Chinese medicine from the method of substance composition of traditional Chinese medicine does not conform to the characteristics of the four-qi of traditional Chinese medicine derived from biological effects. The latter method is in line with the theory of four-qi of traditional Chinese medicine, but the research is based on the research idea of ​​reductionism, which makes the research on the four-qi go to one-sided fragmentation, not in line with the holistic view of TCM

There are some deficiencies in the two methods of judging the four Qi of traditional Chinese medicine

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