A blood streptococcin compound preparation for treating oral candidiasis and preparation method thereof

Abstract

The invention relates to a streptocin compound preparation for treating candidiasis of the oral cavity and a preparation method of the preparation and belongs to the technical field of microorganism pharmacy. The problem is solved that streptocin cannot precisely achieve a medicine effect on the infected part of the mucous membrane of the oral cavity. The streptocin compound preparation for treating candidiasis of the oral cavity is a powder injection for injection to the mucous membrane of the oral cavity. An anti-fungal component streptocin is dispersed in the powder injection in a medicine-loading composite microsphere form, the activity and stability of the streptocin are improved, and the bioavailability of the preparation is improved. Flos lonicerae, radix scrophulariae, radix ophiopogonis and menthol can nourish yin, promote the secretion of saliva or body fluid and relieve the symptoms of the dry and scorching hot oval cavity of patients; sodium alga acid and chitosan are safe,free of toxicity, degradable and good in biocompatibility. According to the streptocin compound preparation, the mucous membrane of the injected part is subjected to injection and dosing, the medicine effect can be precisely achieved, the streptocin directly acts on candida albicans, the local concentration is high, and the effects of lowering adhesive power of the candida albicans and inhibitingand killing the candida albicans can be quickly achieved.

Description

technical field

[0001] The invention belongs to the technical field of microbial pharmacy, and in particular relates to a blood streptococcin compound preparation for treating oral candidiasis albicans and a preparation method thereof. Background technique

[0002] In recent years, due to the abuse of antibiotics, the frequent use of hormones and immunosuppressants, the incidence of Candida has increased year by year. Candida albicans is an opportunistic pathogenic bacterium that exists in the human oral environment. It is highly infectious and can cause a variety of oral mucosal diseases under certain conditions. The change of oral environment will cause the imbalance of flora in the oral cavity, and the key factor of periodontal disease is the imbalance of flora. The long-term persistence of human oral candidiasis indicates that the patient has local or systemic immunocompromise or loss. If antifungal drugs and other treatment measures are not given in time, it will lead ...

Images