Method for identifying sperm fragments in DNA image

A recognition method and technology in images, applied in the field of sperm recognition, can solve problems such as inconsistent conclusions, judgment errors, and inability to quantitatively analyze sperm images

Pending Publication Date: 2019-10-22
SHANGHAI BEION MEDICAL TECH CO LTD
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  • Abstract
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Problems solved by technology

However, there are many disadvantages in the manual microscope inspection method, such as strong subjectivity, inconsistent conclusions made by different operators, and inconsistent conclusions drawn by the same operator at different time periods, resulting in extreme human judgment. Large errors, mainly due to the inability to quantitatively analyze the stained sperm images

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  • Method for identifying sperm fragments in DNA image
  • Method for identifying sperm fragments in DNA image
  • Method for identifying sperm fragments in DNA image

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Embodiment Construction

[0013] In order to make the purpose, technical features and advantages of the present invention more understandable to those in the relevant technical field, and to implement the present invention, the technical features and implementation modes of the present invention are specifically explained in conjunction with the attached drawings, and listed The preferred embodiment is further described. The diagrams compared below are intended to express the schematic representations related to the features of the present invention, and are not and need not be completely drawn according to the actual situation. The description about the implementation of this case involves technical content well known to those skilled in the art, and will not be stated again.

[0014] First please refer to figure 1 , and at the same time cooperate with figure 2 - Figure 4 and Figure 5A - Figure 5B Together to explain. figure 1 According to the technology disclosed in the present invention, i...

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Abstract

The invention discloses a method for identifying sperm fragments in a DNA image. The method comprises the following steps: collecting a sperm image of a sperm sample, carrying out image preprocessingon the sperm image to screen out a plurality of candidate sperms, extracting the contour of the sperm head of each candidate sperm, calculating the nuclear contour and halo contour of the sperm head of each candidate sperm, and calculating the halo contour of the sperm head of each candidate sperm; fitting the radius of the outline of the sperm head of each candidate sperm and classifying each candidate sperm; and classifying DNA fragments of normal sperms and existing sperms from the sperm image. Therefore, a doctor can further analyze the causes of infertility, spontaneous abortion and embryo infertility from the DNA fragments with sperms, and can evaluate and diagnose the outcome of pregnancy and the selection of an auxiliary fertility mode in advance.

Description

technical field [0001] The invention relates to a method for identifying sperm, in particular to a method for identifying sperm fragments in DNA images. Background technique [0002] In recent years, in addition to routine testing of semen, sperm function testing has also received increasing attention in the evaluation of male fertility, especially the testing of sperm DNA integrity. Studies have shown that sperm DNA damage can affect the fertilization rate, embryo quality, clinical pregnancy rate, miscarriage rate, etc. of IVF. [0003] At present, the most commonly used detection methods are sperm chromatin diffusion test SCD method, flow cytometry detection method and acridine orange staining and other methods. At present, most literature reports believe that patients with sperm nuclear DNA fragmentation rate (DFI) > 27% or higher have relatively low fertility. The lower the DFI, the better the integrity of the sperm DNA, and the higher the fertility. ability. [00...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/00G06K9/62
CPCG06T7/0012G06F18/241
Inventor 毛仁建
Owner SHANGHAI BEION MEDICAL TECH CO LTD
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