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Feed additive for relieving endoplasmic reticulum injury of intestinal epithelial cells of IUGR piglets and preparation method and application thereof

A technology of intestinal epithelial cells and feed additives, applied in application, animal feed, animal feed, etc., can solve the problems of intestinal dysplasia, IUGR piglet survival rate, growth rate and feed conversion rate low

Inactive Publication Date: 2019-11-15
YATAI XINGYUAN FARMING TECH HAIAN CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, after IUGR piglets are born, the endoplasmic reticulum of their intestinal epithelial cells is damaged, which will cause their intestinal dysplasia, and metabolic disorders of nutrients such as protein, fat, sugar, etc., resulting in the survival rate, growth rate and feed loss of IUGR piglets. low conversion rate
[0003] At present, there is no specific measure to reduce the endoplasmic reticulum damage of intestinal epithelial cells of IUGR piglets. Therefore, it is of great significance to develop feed additives that can reduce the damage of endoplasmic reticulum of intestinal epithelial cells of IUGR piglets

Method used

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  • Feed additive for relieving endoplasmic reticulum injury of intestinal epithelial cells of IUGR piglets and preparation method and application thereof
  • Feed additive for relieving endoplasmic reticulum injury of intestinal epithelial cells of IUGR piglets and preparation method and application thereof
  • Feed additive for relieving endoplasmic reticulum injury of intestinal epithelial cells of IUGR piglets and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] This embodiment provides a feed additive, which is prepared according to the following preparation method:

[0058] Raw materials were weighed: 0.1 parts by weight of Aralia japonica extract, 4 parts by weight of Polygonatum odoratum extract, 5 parts by weight of rare earth glucosamine chelate salt, and 90.9 parts by weight of defatted rice bran.

[0059] Firstly mix 0.1 parts by weight of Aralia japonica extract and 0.2 parts by weight of defatted rice bran, and then mix uniformly with 4 parts by weight of Polygonatum odoratum extract, 5 parts by weight of rare earth glucosamine chelate salt and 90.7 parts by weight of remaining defatted rice bran, Get feed additives.

Embodiment 2

[0061] This embodiment provides a feed additive, which is prepared according to the following preparation method:

[0062] Raw materials were weighed: 0.3 parts by weight of Aralia japonica extract, 8 parts by weight of Polygonatum odoratum extract, 8 parts by weight of rare earth glucosamine chelate salt, and 83.7 parts by weight of defatted rice bran.

[0063] First mix 0.3 parts by weight of Aralia japonica extract and 0.6 parts by weight of defatted rice bran, and then mix uniformly with 8 parts by weight of Polygonatum odoratum extract, 8 parts by weight of rare earth glucosamine chelate salt and 83.1 parts by weight of the remaining defatted rice bran, Get feed additives.

Embodiment 3

[0065] This embodiment provides a feed additive, which is prepared according to the following preparation method:

[0066] Raw materials were weighed: 0.5 parts by weight of Aralia japonica extract, 12 parts by weight of Polygonatum odoratum extract, 10 parts by weight of rare earth glucosamine chelate salt, and 77.5 parts by weight of defatted rice bran.

[0067] Firstly mix 0.5 parts by weight of Aralia japonica extract and 1 part by weight of defatted rice bran, and then mix uniformly with 12 parts by weight of Polygonatum odoratum extract, 10 parts by weight of rare earth glucosamine chelate salt and 76.5 parts by weight of remaining defatted rice bran, Get feed additives.

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Abstract

The invention provides a feed additive for relieving endoplasmic reticulum injury of intestinal epithelial cells of IUGR piglets and a preparation method and application thereof, and relates to the field of feed additives. The feed additive for reducing endoplasmic reticulum injury of intestinal epithelial cells of IUGR piglets comprises the following raw materials in percentage by mass: 0.1-0.5%of aralia elata extract, 4-12% of polygonatum odoratum extract, 5-10% of rare earth chitosamine chelate salt and the balance of a carrier. The preparation method comprises: uniformly mixing the araliaelata extract with part of the carrier, and mixing the obtained mixture with the polygonatum odoratum extract, the rare earth chitosamine chelate salt and the rest carrier. The application is that the feed additive is added into a creep feed of piglets according to a mass ratio of 0.05-0.15% in the total amount. The feed additive for reducing endoplasmic reticulum injury of intestinal epithelialcells of IUGR piglets is used for reducing endoplasmic reticulum injury of intestinal epithelial cells of IUGR piglets, and improving survival rate, growth speed and feed conversion rate of the IUGR piglets.

Description

technical field [0001] The present application relates to the field of feed additives, in particular, to a feed additive for alleviating endoplasmic reticulum damage of intestinal epithelial cells of IUGR piglets and its preparation method and application. Background technique [0002] In the pig industry, the incidence of IUGR (intrauterine growth retardation, intrauterine growth retardation) piglets is relatively high. Under pathological conditions of IUGR piglets, such as nutrient deficiency, redox, glycosylation, and calcium mobilization disorders, etc., the protein folding capacity of the endoplasmic reticulum will be overloaded, causing endoplasmic reticulum stress, resulting in endoplasmic reticulum stress. The endoplasmic reticulum is the main site for the synthesis, folding, modification and sorting of endocrine and transmembrane proteins in eukaryotic cells. Therefore, after IUGR piglets are born, the endoplasmic reticulum of their intestinal epithelial cells is d...

Claims

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Application Information

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IPC IPC(8): A23K50/30A23K10/30A23K20/20A01K67/02
CPCA01K67/02A23K10/30A23K20/30A23K50/30Y02P60/87
Inventor 王丽娜李同刚樊倩朱小清袁香丽陈志敏仲伟迎吴有林
Owner YATAI XINGYUAN FARMING TECH HAIAN CO LTD