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A lesion classification system based on deep learning and probabilistic radiomics

A deep learning and radiomics technology, which is applied in the field of lesion classification system and lesion CT image classification, can solve the problems of insufficient classification accuracy, ambiguity of lesion classification, lack of controllability and transparency, etc.

Active Publication Date: 2020-01-07
点内(上海)生物科技有限公司
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Problems solved by technology

However, first of all, the method adopted by this patent is based on a 2D convolutional neural network, which makes this patent not capable of capturing three-dimensional spatial features
Secondly, the patent uses traditional black-box deep learning, which makes the patented technology not controllable and transparent
There is also the problem of ambiguity caused by classification fuzziness.
[0010] Therefore, it is urgent to propose a new classification system to solve the problem of ambiguity and insufficient classification accuracy caused by the ambiguity of classification of lesions in the existing classification technology.

Method used

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  • A lesion classification system based on deep learning and probabilistic radiomics
  • A lesion classification system based on deep learning and probabilistic radiomics
  • A lesion classification system based on deep learning and probabilistic radiomics

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Embodiment 1

[0053] In this embodiment, the present invention proposes a lesion classification system for classifying lung CT images of pulmonary nodules. The scope of application of the present invention is not limited to pulmonary nodules, and is also applicable to the classification of other lesions (such as masses, etc.).

[0054] The overall framework of the lesion classification system based on deep learning and probabilistic radiomics proposed by the present invention is as follows: figure 1 shown, including:

[0055] Data collection module: using the public lung nodule dataset LIDC-IDRI (Armato SG III, et al.: The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): A completed reference database of lung nodules on CT scans. MedicalPhysics, 38: 915--931, 2011), the public data set contains 2635 nodules, each of which is labeled by 4 experienced radiologists, and all 2635 nodules are identified by 4 doctors The same lesion is classified and segmente...

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Abstract

The invention relates to a lesion classification system based on deep learning and probabilistic radiomics, belonging to the technical field of medical image classification. Aiming at the problems of ambiguity and low classification accuracy caused by the ambiguity of the existing lesion classification system, the present invention uses the deep convolutional neural network as the backbone, and proposes a non-local shape analysis module to extract the feature cloud of the lesion on the medical image. , remove the interference of the surrounding pixels of the lesion on the classification judgment, and obtain the essential representation of the lesion; at the same time, in order to capture the ambiguity of the label, a fuzzy prior network is proposed to simulate the fuzzy distribution of different expert labels, showing that the ambiguity of the expert label is modeled, The classification results of model training are more robust, and a new lesion classification system is constructed by combining fuzzy prior samples with lesion representation, which is controllable and probabilistic, compared with traditional convolutional neural networks. The network can better solve the problem of classification ambiguity and obtain higher classification accuracy.

Description

technical field [0001] The invention relates to the classification technology of CT images of lesions, in particular to a lesion classification system based on deep learning and probabilistic radiomics, and belongs to the technical field of medical image classification. Background technique [0002] At present, the morbidity and mortality of various cancers in China rank first among all kinds of diseases, among which the morbidity and mortality of lung cancer rank first among various malignant tumors, posing a huge threat to people's health. Pulmonary nodule screening is an important means to achieve early diagnosis and treatment of lung cancer. The radiomics analysis method uses doctors to manually outline regions of interest, image processing, feature extraction, and feature screening, and then combines machine learning algorithms to predict target variables and assist doctors to analyze lesions. It has powerful functions and has been widely used. Compared with traditiona...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06K9/62G06T7/00G06N3/04G06N3/08
CPCG06T7/0012G06N3/084G06T2207/10081G06T2207/30096G06T2207/20081G06T2207/20084G06T2207/20104G06N3/045G06F18/2415G06F18/214
Inventor 杨健程方荣耀葛亮
Owner 点内(上海)生物科技有限公司
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