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Focus classification system based on deep learning and probability imaging omics

A deep learning and radiomics technology, applied in the field of lesion CT image classification and lesion classification system, which can solve the problems of ambiguous ambiguity in lesion classification, insufficient classification accuracy, and inability to eliminate ambiguity in classification.

Active Publication Date: 2019-11-15
点内(上海)生物科技有限公司
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Problems solved by technology

However, first of all, the method adopted by this patent is based on a 2D convolutional neural network, which makes this patent not capable of capturing three-dimensional spatial features
Secondly, the patent uses traditional black-box deep learning, which makes the patented technology not controllable and transparent
There is also the problem of ambiguity caused by classification fuzziness.
[0010] Therefore, it is urgent to propose a new classification system to solve the problem of ambiguity and insufficient classification accuracy caused by the ambiguity of classification of lesions in the existing classification technology.

Method used

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  • Focus classification system based on deep learning and probability imaging omics
  • Focus classification system based on deep learning and probability imaging omics
  • Focus classification system based on deep learning and probability imaging omics

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Embodiment 1

[0053] In this embodiment, the present invention proposes a lesion classification system for classifying lung CT images of pulmonary nodules. The scope of application of the present invention is not limited to pulmonary nodules, and is also applicable to the classification of other lesions (such as masses, etc.).

[0054] The overall framework of the lesion classification system based on deep learning and probabilistic radiomics proposed by the present invention is as follows: figure 1 shown, including:

[0055] Data collection module: using the public lung nodule dataset LIDC-IDRI (Armato SG III, et al.: The LungImage Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): A completed reference database of lung nodules on CT scans. MedicalPhysics, 38: 915--931, 2011), the public data set contains 2635 nodules, each of which is labeled by 4 experienced radiologists, and all 2635 nodules are identified by 4 doctors The same lesion is classified and segmented...

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Abstract

The invention relates to a focus classification system based on deep learning and probability imaging omics, and belongs to the technical field of medical image classification. The objective of the invention is to solve problems of ambiguity caused by classification ambiguity and low classification precision of an existing lesion classification system. According to the method, a deep convolutionalneural network is used as a main stem, a non-local shape analysis module is proposed to extract feature cloud of a focus on a medical image, interference of pixels around the focus on classificationjudgment is removed, and essential representation of the focus is obtained; meanwhile, the fuzziness of the label is captured; a fuzzy prior network is provided to simulate fuzzy distribution of different expert labels; ambiguity of expert annotation is displayed and modeled; the classification result of model training has better robustness, the fuzzy prior sample is combined with focus representation, a new focus classification system is constructed and can achieve controllability and probability; compared with a traditional convolutional neural network, a classification fuzziness problem isbetter solved, and higher classification precision can be acquired.

Description

technical field [0001] The invention relates to the classification technology of CT images of lesions, in particular to a lesion classification system based on deep learning and probabilistic radiomics, and belongs to the technical field of medical image classification. Background technique [0002] At present, the morbidity and mortality of various cancers in China rank first among all kinds of diseases, among which the morbidity and mortality of lung cancer rank first among various malignant tumors, posing a huge threat to people's health. Pulmonary nodule screening is an important means to achieve early diagnosis and treatment of lung cancer. The radiomics analysis method uses doctors to manually outline regions of interest, image processing, feature extraction, and feature screening, and then combines machine learning algorithms to predict target variables and assist doctors to analyze lesions. It has powerful functions and has been widely used. Compared with traditiona...

Claims

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Application Information

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IPC IPC(8): G06K9/62G06T7/00G06N3/04G06N3/08
CPCG06T7/0012G06N3/084G06T2207/10081G06T2207/30096G06T2207/20081G06T2207/20084G06T2207/20104G06N3/045G06F18/2415G06F18/214
Inventor 杨健程方荣耀葛亮
Owner 点内(上海)生物科技有限公司
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