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Ameliorative or preventive agent for inflammatory bowel disease and / or immune disorders

A technology for inflammatory bowel disease and immune abnormalities, applied in the field of improving or preventing agents and lipid metabolism improving agents, can solve problems such as no research on intestinal bacteria, achieve excellent improvement or prevention effect, excellent safety, lipid metabolism Excellent improvement effect

Active Publication Date: 2019-12-10
DAICEL CHEM IND LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no research on increasing intestinal bacteria including short-chain fatty acid producing bacteria other than lactic acid drinks etc.

Method used

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  • Ameliorative or preventive agent for inflammatory bowel disease and / or immune disorders
  • Ameliorative or preventive agent for inflammatory bowel disease and / or immune disorders
  • Ameliorative or preventive agent for inflammatory bowel disease and / or immune disorders

Examples

Experimental program
Comparison scheme
Effect test

manufacture example 1

[0186] 5.1 parts by weight of acetic acid and 2.0 parts by weight of water were added to 1 part by weight of cellulose acetate (manufactured by Daicel, trade name "L-50", total degree of acetyl substitution: 2.43, 6% viscosity: 110 mPa·s), Stirring at 40°C for 5 hours gave a solution that was homogeneous in appearance. To this solution, 0.13 parts by weight of sulfuric acid was added, and the resulting solution was kept at 70°C for hydrolysis (partial deacetylation reaction; aging). In addition, in this ripening process, water was added to the system twice halfway. That is, 0.67 parts by weight of water was added 1 hour after the start of the reaction, and 1.67 parts by weight of water was added after another 2 hours, followed by further reaction for 6 hours. The total hydrolysis time was 9 hours. It should be noted that from the beginning of the reaction to the addition of the first water is called the first aging, from the addition of the first water to the addition of the...

Embodiment 1

[0229] Using the water-soluble cellulose acetate obtained in Production Example 1, each component was mixed so as to have the composition described in Table 1, and a powdery nutritional composition having an effect of improving lipid metabolism was prepared.

reference example 1

[0233] Using indigestible dextrin "Pine Fiber" manufactured by Matsutani Chemical Industry Co., Ltd., each component was mixed so as to have the composition described in Table 1, and a powdery nutritional composition was prepared.

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Abstract

The invention provides a cellulose acetate with a total degree of substitution of acetyl ranging from 0.4 to 1.1. The cellulose acetate is used for the preparation of an agent for improving or preventing inflammatory bowel disease and / or immune disorders.

Description

[0001] This application is a divisional application of an invention patent application filed on March 24, 2014 with the application number 201480069816.8 (PCT application number PCT / JP2014 / 058069) and the invention title "Nutritional Composition with Lipid Metabolism Improvement" . technical field [0002] The present invention relates to a nutritional composition having an effect of improving lipid metabolism. The nutritional composition can exert an excellent effect of reducing neutral fat. In addition, preventive and ameliorating effects on obesity, hyperlipidemia, and the like can be expected. The present invention also relates to an agent for improving lipid metabolism, and an agent for improving or preventing inflammatory bowel disease and / or immune abnormality (allergic disease, etc.). This application claims priority based on Japanese Patent Application No. 2013-263889 for which it applied in Japan on December 20, 2013, and uses the content here. Background techniq...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/717A61P1/00A61P37/02A23L33/24A23K20/163
CPCA23K20/163A23K50/10A23K50/30A23K50/75A23L33/24A61K31/717A61K45/06A61P1/00A61P1/04A61P1/16A61P3/04A61P3/06A61P3/10A61P35/00A61P37/02C08B3/06C08B3/24C08B3/28C08L1/12C08L1/14A61K2300/00A23K50/40A23V2002/00
Inventor 岛本周中村敏和浮田静中村强山内良子小林弘司
Owner DAICEL CHEM IND LTD