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Traditional Chinese medicine composition and application of traditional Chinese medicine composition to regulation of intestinal microorganisms

A technology for regulating intestinal tract and composition, applied in traditional Chinese medicine composition, improving and regulating intestinal microbes in the field of use, can solve problems such as influence

Pending Publication Date: 2019-12-27
ZHUHAI QLWEL BIO TECH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although it is not clear whether the changes in the gut microbiota cause the occurrence of metabolic diseases, or the occurrence of metabolic diseases leads to the changes in the gut microbiota, but one thing is certain: by changing the gut microbiota The composition of the group has an impact on the health of the human body, and may also help the treatment of certain diseases

Method used

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  • Traditional Chinese medicine composition and application of traditional Chinese medicine composition to regulation of intestinal microorganisms
  • Traditional Chinese medicine composition and application of traditional Chinese medicine composition to regulation of intestinal microorganisms
  • Traditional Chinese medicine composition and application of traditional Chinese medicine composition to regulation of intestinal microorganisms

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The preparation of embodiment 1 Chinese medicine composition powder

[0047] Prescription: Astragalus 60g, Polygonatum 40g, Angelica 40g, Panax notoginseng 12g, Rhizoma Imperatae 40g, Rhubarb Charcoal 10g, Curcuma 40g, Zhebei 30g, Barley 30g, Pinellia 30g.

[0048] Chinese medicine decoction pieces including astragalus, sealwort, angelica, notoginseng, rhubarb rhubarb, turmeric, zhebei, barley, and pinellia were all purchased from Guangdong Provincial Hospital of Traditional Chinese Medicine. The corresponding prescription doses were put into a low-temperature drying box Drying, temperature range: 30-40°C, humidity range: 10-20%RH, so that the surface moisture of the drug is ≤0.5%, and then the dried drug is input into the pulverizer while it is hot for pulverization, pulverized to 900 mesh, and The powder is sterilized and vacuum-packed for use.

Embodiment 2

[0049] Embodiment 2 ethanol extraction method prepares Chinese medicine composition extract

[0050] Prescription: Astragalus 15g, sealwort 10g, angelica 10g, notoginseng 6g, rhubarb root 20g, rhubarb charcoal 3g, turmeric 10g, zhebei 10g, barley 10g, French pinellia 10g.

[0051] Take the drug corresponding to the prescription dose, crush the drug into 20-mesh drug powder, extract the coarse drug powder three times with 80% ethanol solution, filter the extract and concentrate under reduced pressure to obtain a drug concentrate, and elute the concentrate through an adsorption column. The packing of the adsorption column is HPD100, which is firstly washed with purified water to remove impurities, and then eluted with 60%, 70%, and 80% ethanol to obtain an eluate, which is concentrated under reduced pressure, decolorized, refined, and concentrated under reduced pressure to immersion Paste, after freeze-drying to obtain the extract of traditional Chinese medicine composition.

Embodiment 3

[0052] Embodiment 3 water decocting method prepares Chinese medicine composition extract

[0053] Prescription: Astragalus 30g, Polygonatum 20g, Angelica 20g, Panax notoginseng 9g, Rhizoma Imperatae 30g, Rhubarb Charcoal 6g, Curcuma 20g, Zhebei 15g, Barley 15g, Pinellia 15g.

[0054] Take the medicine with the corresponding prescription dose, put it in a suitable decocter, add about 600ml of water to immerse the medicinal material for 1 hour, boil it and heat it for 0.5 hour, separate and decoct the liquid, and decoct the drug dregs for the second time according to the law, the decocted liquid is the same as the first decocted liquid Mix and measure the volume with a measuring cylinder. If the volume exceeds 600ml, further boil the decoction and concentrate it to about 600ml. After reaching the corresponding volume, boil the decoction and vacuum pack it into 7-8 small bags, and store it at 4°C for later use. use.

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Abstract

The invention provides a traditional Chinese medicine composition, application of the traditional Chinese medicine composition to regulation of intestinal microorganisms and application of the traditional Chinese medicine composition to medicine preparation. The traditional Chinese medicine composition is prepared from a medicine for reinforcing qi and nourishing blood, a medicine for cooling blood and stopping bleeding and a medicine for resolving phlegm and resolving stasis. The medicines are used for treating diseases related to intestinal flora disturbance.

Description

technical field [0001] The invention belongs to the field of medicine and health care, and in particular relates to the application of a traditional Chinese medicine composition in improving and regulating intestinal microorganisms. Background technique [0002] There are a large number of symbiotic microorganisms in the human body, especially 1000-1150 kinds of about 100 trillion bacteria in the human intestinal tract, which are the most important "endogenous environmental factors" of the human body, and the number of them is about 10 times that of the human body's own cells. Under normal circumstances, intestinal microorganisms are in a dynamic and balanced ecological environment. Normal flora not only play an irreplaceable role in digestion, immunity and anti-virus, but also changes in intestinal microorganisms are closely related to body health or diseases, especially some chronic diseases. The occurrence of disease has a very close relationship. In the contemporary soc...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61K36/9066A61P1/00A61P1/12A61P1/10A61P3/04A61P37/08A61P1/18A61P1/16A61P29/00A61P1/04A61P13/06A61P3/10A61P19/02A61P9/00A61P9/10A61P35/00A61P25/02A61P27/02A61P37/02A61P1/08A61P25/16A61P25/22A61P25/00A61P25/24A61P39/00A61K33/44
CPCA61K33/44A61K36/232A61K36/258A61K36/481A61K36/708A61K36/8888A61K36/8966A61K36/8969A61K36/899A61K36/8994A61K36/9066A61K45/06A61P1/00A61P1/04A61P1/08A61P1/10A61P1/12A61P1/16A61P1/18A61P3/04A61P3/10A61P9/00A61P9/10A61P13/06A61P19/02A61P25/00A61P25/02A61P25/16A61P25/22A61P25/24A61P27/02A61P29/00A61P35/00A61P37/02A61P37/08A61P39/00A61K2300/00Y02A50/30
Inventor 魏来梁桥星葛小菲
Owner ZHUHAI QLWEL BIO TECH LTD
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