Method for preparing Florfenicol soluble powder medicine

Abstract

The invention discloses a method for preparing a Florfenicol soluble powder medicine, and relates to the technical field of veterinary medicines. The Florfenicol soluble powder medicine comprises thefollowing ingredients: Florfenicol, anhydrous citric acid, trimethoprim lactate, and anhydrous glucose. The preparation method of the Florfenicol soluble powder medicine disclosed by the invention comprises the following steps: weighing the Florfenicol, the anhydrous citric acid and the trimethoprim lactate, and carrying out crushing and sieving so as to obtain crushed materials; adding the anhydrous glucose, at an amount equal to the total weight of the three crushed materials, and carrying out premixing by adopting a dispersion means for 15 minutes so as to obtain a premix; and then, fully mixing the premix with the remaining anhydrous glucose for 1 hour so as to achieve uniform mixing, thereby obtain the Florfenicol soluble powder medicine. The Florfenicol soluble powder medicine prepared by the preparation method can be quickly dissolved with water so as to achieve the purpose of solubility; and moreover, the Florfenicol soluble powder medicine has the advantages of being convenient to administrate and capable of yielding faster results. In addition, the Florfenicol is adopted in combination with the synergists, so that overall treatment effects of the Florfenicol soluble powder medicine are enhanced, thereby having efficacy improved.

Description

technical field [0001] The invention relates to the technical field of veterinary drugs, in particular to a florfenicol soluble powder drug. Background technique [0002] Florfenicol is a third-generation florfenicol broad-spectrum antibacterial drug for veterinary medicine, mainly used for the prevention and treatment of bacterial diseases such as livestock, poultry and fish caused by sensitive bacteria. [0003] Florfenicol has low solubility and is a water-insoluble powder, which affects the development of its soluble powder to a certain extent. Its absorption and bioavailability in animals are low, and it is often administered by mixing it into feed. The route of administration is single, which limits the full play of the drug effect. Due to the inconvenient administration, the appetite is lost when poultry and livestock get sick, often resulting in poor curative effect, which is also unfavorable for its popularization and application in breeding production. Contents o...

AI Technical Summary

Problems solved by technology

[0003] Florfenicol has low solubility and is a water-insoluble powder, which affects the development of its soluble powder to a certain extent. Its absorption and bioavailability in animals are low, and it is often administered by mixing it into feed. The route of administration is single, which limits the full play of the drug effect. Due to the inconvenient administration, the appetite is lost when the poultry and livestock get sick, often resulting in poor curative effect, which is also unfavorable for its popularization and application in breeding production.

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