Synbiotics and application thereof

A technology of synbiotics and prebiotics, applied in synbiotics and its application fields, can solve the problem of insufficient immunity contribution, and achieve the effect of synergistically enhancing immunity, increasing white blood cells, and improving lymphocyte transformation rate.

Inactive Publication Date: 2020-06-12
广东量子高科微生态医疗有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the products currently on the market are only for the purpose of supplementing probiotics, and their contribution to improving immunity is not outstanding. Therefore, it is imminent to develop a product that can significantly maintain intestinal health and improve immunity

Method used

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  • Synbiotics and application thereof
  • Synbiotics and application thereof
  • Synbiotics and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1 of the present invention is: a solid beverage prepared by mixing the following raw materials in equal parts by weight: fructo-oligosaccharide 20; galacto-oligosaccharide 35; stachyose 20; probiotic powder 5: Tremella polysaccharide 10; Hericium erinaceus instant powder 3; Strawberry fruit powder 6; Calcium silicate 1.

[0026] Embodiment 2 of the present invention is: a solid beverage prepared by mixing the following raw materials in equal parts by weight: fructo-oligosaccharide 30; galacto-oligosaccharide 53; stachyose 5; probiotic powder 4: tremella polysaccharide 4; Hericium erinaceus instant powder 0.7; strawberry fruit powder 3; calcium silicate 0.3.

[0027] In the above examples, the probiotic powder is composed of Lactobacillus acidophilus NCFM, Bifidobacterium lactis HN019, Lactobacillus paracasei Lpc-37 and Lactobacillus rhamnosus HN001, and the addition ratio is (4-6): (0.5-1 ): (1.5-3.0): (0.7-1.2) and the number of live bacteria is >10 10 CFU...

Embodiment 1

[0033] Example 1 group: 10 times the human dose (10g / 60kg·d) of the synbiotic solid beverage prepared in Example 1 by intragastric administration;

Embodiment 2

[0034] Example 2 group: 10 times the human dose (10g / 60kg d) of the synbiotic solid beverage prepared in Example 2 by intragastric administration;

[0035] After feeding for 10 days, take 0.1g of mouse feces, extract fecal DNA, and use 16s rRNA high-throughput sequencing technology to detect the intestinal flora in mouse feces. The results are as follows: Figure 1~2Shown; The number of Bifidobacteria and Enterobacteriaceae in flora was detected by fluorescent quantitative method, and the results were as follows image 3 shown. from Figure 1~2 It can be seen that, compared with the control group, the solid beverage combined with synbiotics of the present invention can change the structure of the intestinal flora of mice, increase the relative proportion of beneficial bacteria Bifidobacterium in the intestinal tract of mice, and reduce the intestinal bacterium of conditional pathogenic bacteria. The relative proportion of bacilli. from image 3 It can be seen from the figu...

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Abstract

The invention discloses synbiotics and application thereof. The synbiotics comprise prebiotics and probiotic powder, wherein the prebiotics comprise oligosaccharide, stachyose, tremella polysaccharideand hericium erinaceus instant powder; and the probiotic powder includes lactobacillus acidophilus NCFM, bifidobacterium lactis HN019, lactobacillus paracasei Lpc-37 and lactobacillus rhamnosus HN001. The synbiotics provided by the scheme of the invention can supplement intestinal probiotics and prebiotics and improve gastrointestinal tract health; meanwhile, the immunity of the human body can beimproved, the safety of all the components is high, and prebiotics and probiotics are added at the same time so that the intestinal health can be maintained, and the immunity is improved.

Description

technical field [0001] The invention relates to the technical field of food, in particular to a synbiotic and its application. Background technique [0002] Synbiotics refers to the combined use of probiotics and prebiotics (mainly various dietary fibers). Probiotics refer to the flora that are beneficial to the human body and can improve the microecology of the human body. Common intestinal probiotics include bifidobacteria, lactobacilli, etc. Probiotics can (1) adjust the intestinal flora and inhibit the growth of pathogenic bacteria; (2) adjust the immune response, treat food allergy and inflammatory bowel disease, etc.; (3) protect the intestinal barrier function of postoperative patients and reduce infection (4) Preventive and therapeutic effects in the occurrence and development of tumors; (5) Lower serum cholesterol, improve digestion and other probiotic functions. Prebiotics refer to food ingredients that can be used as fermentation substrates to promote the growth...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/25A23L33/21A23L33/135A23L31/00A23L2/38
CPCA23L33/25A23L33/21A23L33/135A23L31/00A23L2/38A23V2002/00A23V2400/165A23V2400/175A23V2400/113A23V2400/531A23V2200/3204A23V2200/3202A23V2200/324A23V2250/28A23V2250/632A23V2250/51A23V2200/14
Inventor 李志鹏刘梦莹廖瑜玲苏丽丽
Owner 广东量子高科微生态医疗有限公司
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