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Squalene oxygen injection composition and application thereof

A composition, squalene technology, applied in the directions of drug combination, cosmetic preparations, medical preparations containing active ingredients, etc., can solve problems such as weak activity, irritation, weakening of vaginal repair function, etc. Effects of oxygen status, reduced irritation, and optimal storage stability

Inactive Publication Date: 2020-07-17
山东川云生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patent CN108452295A discloses a firming gel that inhibits bacteria and regulates micro-ecological balance and its preparation method. Plant extracts such as honeysuckle extract and cnidium extract are used in combination with nano-silver, which has a strong ability to kill vaginal harmful substances. However, the anti-inflammatory and bactericidal activity of traditional Chinese medicine using plant extracts as the main component for female genitals is not strong. Although the combination of nano-silver and other inorganic substances will enhance the bactericidal effect, it should be used on sensitive parts for a long time It will cause certain irritation and weaken the vagina's own repair function

Method used

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  • Squalene oxygen injection composition and application thereof
  • Squalene oxygen injection composition and application thereof
  • Squalene oxygen injection composition and application thereof

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preparation example Construction

[0082] The fourth aspect of the present invention provides a preparation method of squalene oxygen injection gel, the steps at least include: adding the squalene oxygen injection composition, a pH regulator, a cooling agent, a solubilizer, and a moisturizing agent , deionized water to mix evenly.

[0083] In some preferred embodiments, the preparation method of the squalene oxygen injection gel, the steps at least include:

[0084] (1) Add acrylic acid (ester) / C10-30 alkanol acrylate crosslinked polymer to 40-50wt% part of deionized water, soak for 25-35min, heat at 50-60°C and stir evenly to obtain the first pre-dissolved solution;

[0085] (2) Stir the pH regulator and the 1-5 wt% part in deionized water evenly to obtain the second pre-dissolved solution;

[0086] (3) Pre-dissolve the pulsatilla extract and the 1-5 wt% part in deionized water to obtain the third pre-dissolved solution; heat and melt the cooling agent, add a solubilizer, a humectant, and a lactic acid bacte...

Embodiment 1

[0101] A squalene oxygen injection composition, in parts by weight, the raw materials at least include: 3 parts of plant extracts, 1.5 parts of skin conditioner, 0.65 parts of compound essential oil, 1.2 parts of lactic acid bacteria fermentation products; the skin conditioner is squalene alkene.

[0102] The plant extract includes a first plant extract and a second plant extract, and the weight ratio of the first plant extract and the second plant extract is 1:1.

[0103] The first plant extract comprises a combination of Phellodendron barkberry extract, Lonicera japonica extract, Fructus Lonicerae extract, Fructus Cnidii extract, and Sophora flavescens extract; The weight ratio of the fruit, the extract of Cnidium Fructus Cnidii and the extract of Sophora flavescens is 1:1.5:1:1.5:2.5.

[0104] The second plant extract comprises a combination of Pulsatillae extract, Salvia extract, Camellia seed extract, and Coix seed extract; the weight ratio of the Pulsatilla extract, Sal...

Embodiment 2

[0119] A squalene oxygen injection composition, in parts by weight, the raw materials at least include: 2 parts of plant extracts, 1 part of skin conditioner, 0.5 part of compound essential oil, 1 part of lactic acid bacteria fermentation product; the skin conditioner is squalene alkene.

[0120] The plant extract includes a first plant extract and a second plant extract, and the weight ratio of the first plant extract and the second plant extract is 1:0.5.

[0121] The first plant extract comprises a combination of Phellodendron barkberry extract, Lonicera japonica extract, Fructus Lonicerae extract, Fructus Cnidii extract, and Sophora flavescens extract; The weight ratio of the fruit, the extract of Cnidium Fructus and the extract of Sophora flavescens is 1:1.2:0.8:1.2:2.

[0122] The second plant extract comprises a combination of Pulsatillae extract, Salvia extract, Camellia seed extract, and Coix seed extract; the weight ratio of the Pulsatilla extract, Salvia extract, C...

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Abstract

The invention relates to the technical field of daily chemical products for feminine hygiene and health, and specifically provides a squalene oxygen injection composition. The composition at least comprises the following raw materials in parts by weight: 2-8 parts of plant extracts, 1-3 parts of a skin conditioner, 0.3-1.5 parts of compound essential oil, and 0.5-2.5 parts of a lactic acid bacteria fermentation product, wherein the skin conditioner at least includes squalene. The invention also provides a squalene oxygen injection gel containing the composition and a preparation method of thegel. The gel has an obvious curative effect on gynecological inflammations such as vaginal itching and trichomonal vaginitis, has a stronger killing effect on pathogenic bacteria such as staphylococcus aureus, escherichia coli and candida albicans, can obviously improve the hypoxic state of body cells, and can timely convey oxygen in blood to the cells to activate the body functional cells.

Description

technical field [0001] The invention relates to the technical field of daily chemical products for women's hygiene and health, and more specifically relates to a squalene oxygen injection composition and its application. Background technique [0002] Lactobacillus is a kind of lactic acid bacteria. It is a probiotic that exists in the human body. It is a huge flora. Harmful bacteria are also a large flora. When probiotics are dominant (accounting for more than 80% of the total), The human body maintains a healthy state, otherwise it is in a sub-healthy or unhealthy state. Lactobacillus is considered to be the safest strain and the most representative probiotic. Therefore, increasing the beneficial flora can help restore the balance of vaginal flora in women, enhance immunity and resistance, and at the same time maintain the acidic environment of the vagina ( pH ≤ 4.5, mostly 3.8-4.4), inhibit the growth of other pathogenic bacteria, and effectively prevent bacterial infecti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/31A61K8/99A61K8/9794A61K8/9789A61K8/92A61K8/04A61Q19/10A61Q19/00A61P15/02A61P17/04A61P33/02A61P31/02A61P31/04A61P31/10
CPCA61K8/042A61K8/31A61K8/922A61K8/99A61K2800/592A61K2800/5922A61K2800/78A61K2800/782A61Q19/00A61Q19/10A61K8/9789A61K8/9794A61P15/02A61P17/04A61P31/02A61P31/04A61P31/10A61P33/02Y02A50/30
Inventor 于秀华韦安迪
Owner 山东川云生物科技有限公司
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