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Dynamic cell impedance imaging device

An impedance imaging and dynamic impedance technology, applied in medical science, sensors, diagnostic recording/measurement, etc., can solve the problem of not having abnormal particle imaging, etc.

Active Publication Date: 2020-08-18
BEIHANG UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But existing electrical impedance tomography (EIT) equipment does not yet have the capability to image abnormal particles in flowing liquids

Method used

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  • Dynamic cell impedance imaging device
  • Dynamic cell impedance imaging device
  • Dynamic cell impedance imaging device

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Embodiment Construction

[0035] In order to facilitate those of ordinary skill in the art to understand and implement the present invention, the present invention will be further described in detail and in-depth below in conjunction with the accompanying drawings.

[0036] The invention is a dynamic cell impedance imaging device, which takes an electrical impedance tomography imager as the main body, synthesizes (refers to) the core technology of the microfluidic single-cell resistance detection system, and completes the capture of abnormal tiny particles in the flowing liquid.

[0037] Such as figure 1 As shown, it consists of three main parts: a dynamic impedance imaging sensor, an impedance detection and flow velocity measurement module, and an electrical impedance tomography instrument. The dynamic impedance imaging sensor includes an annular electrical signal receiver 27, an annular electrical signal receiver 30 and an annular 16-channel imaging sensor 33; the flowing liquid (usually normal salin...

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Abstract

The invention discloses a dynamic cell impedance imaging device, which belongs to the technical field of electrical impedance tomography, and particularly comprises a dynamic impedance imaging sensor,an impedance detection and flow velocity measurement module and an electrical impedance tomography imager, when liquid containing abnormal particles flows through the two annular electric signal receivers in the dynamic impedance imaging sensor, the abnormal particles are detected. The impedance detection and flow velocity measurement module performs detection to generate pulse signals P1 and P2respectively; calculating flow velocity information v of the abnormal particles; when the liquid containing abnormal particles reaches the annular 16-channel imaging sensor, the abnormal particles areimaged. The pulse signal P2 triggers and starts the electrical impedance tomography imager, sine excitation current is generated and injected into the annular 16-channel imaging sensor through the analog switch array, and voltage data V is calculated by adopting the principle of adjacent excitation and adjacent measurement so as to complete inversion imaging and display the inversion imaging. Abnormal particles in flowing liquid are imaged, and good medical prospects are achieved.

Description

technical field [0001] The invention relates to the application of electrical impedance tomography (EIT) in dynamic cell imaging, in particular to a dynamic cell impedance imaging device. Background technique [0002] Electrical impedance tomography (EIT), as a low-cost, non-destructive and radiation-free imaging technique, has been widely used in lung detection, drug detection and static imaging of cancer cell clusters. But existing electrical impedance tomography (EIT) equipment does not yet have the ability to image abnormal particles in flowing liquids. [0003] Imaging of abnormal particles in flowing liquid has good medical prospects: for example, imaging of cancer cell clusters in blood can be used to judge the occurrence of early cancer and whether cancer has metastasized and spread, and imaging of abnormal particles in blood can also assist Determine whether there is an embolism in the blood vessel. Contents of the invention [0004] Aiming at the problem that t...

Claims

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Application Information

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IPC IPC(8): A61B5/053
CPCA61B5/0536
Inventor 孙江涛白旭田文斌谢跃东徐立军
Owner BEIHANG UNIV