Preparation method of throat clearing preparation

A throat-clearing and preparation technology, which is applied in the field of medicine, can solve problems such as poor stability, unqualified thin-layer identification of salicymus root, and scrapping of materials in batches, so as to improve product stability, detection rate and petogenin content , Improve the effect of curative effect and stability

Active Publication Date: 2020-09-22
GUIZHOU YIBAI WOMAN BIG PHARMA FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the Thin-Layer Identification of Salicylic Mylarus root is often unqualified in the Yanhou Qinghou Dropping Pills produced by the existing technology, which leads to the scrapping of materials in batches, and also has poor stability during storage. Therefore, further research is urgently needed to improve the Yanhou Qinghou Dropping Pills preparation process

Method used

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  • Preparation method of throat clearing preparation
  • Preparation method of throat clearing preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Example 1: Weigh 527.5g of nine-headed lion grass, 315g of cinnabar root, 395g of salivarius root, 395g of glutinous rice vine root, 157.5g of golden fruit, 315g of platycodon grandiflorum, 395g of mint and other 7 medicinal materials, divided into 3 equal parts, one part Add 6.7L of water to extract twice, 1 hour each time, combine the extracts, concentrate under reduced pressure, and dry to obtain extract powder 1; add 3.3L of 70% ethanol to extract twice, each time for 1 hour, combine the extracts, and recover the ethanol Concentrate and dry to obtain extract powder 2; add 1.7L of ethyl acetate for ultrasonic extraction twice for 1 hour each time, combine the extracts, recover ethyl acetate, concentrate and dry to obtain extract powder 3, and then add 3 3.8 times the weight of the extract powder was added with polyethylene glycol 4000, heated and melted, and sprayed into menthol ethanol solution (12.5g of menthol was dissolved in 30ml of 75% ethanol), stirred evenly, ...

Embodiment 2

[0066] Example 2: Weigh 527.5g of nine-headed lion grass, 315g of cinnabar root, 395g of salivarius root, 395g of glutinous rice vine root, 157.5g of golden fruit, 315g of platycodon grandiflorum, 395g of mint and other 7 medicinal materials, and divide them into 3 equal parts on average. Add 8.3L of water to extract twice, 1 hour each time, combine the extracts, concentrate under reduced pressure, and dry to obtain extract powder 1; add 5L of 70% ethanol to extract twice, each time for 1 hour, combine the extracts, recover ethanol and Concentrate and dry to obtain extract powder 2; add 2.5L of ethyl acetate for ultrasonic extraction twice, each time for 1 hour, combine the extracts, recover ethyl acetate, concentrate and dry to obtain extract powder 3, and then add 3 parts Mix the extract powder evenly, add polyethylene glycol 4000 in an amount of 4 times the weight of the extract powder, heat and melt, spray 25ml of peppermint oil, stir evenly, and drop into pills.

Embodiment 3

[0067] Example 3: Weigh 527.5g of nine-headed lion grass, 315g of cinnabar root, 395g of salivarius root, 395g of glutinous rice vine root, 157.5g of golden fruit, 315g of platycodon grandiflorum, 395g of mint and other 7 medicinal materials, and divide them into 3 equal parts on average. Add 6.7L of water to extract twice, 2 hours each time, combine the extracts, concentrate under reduced pressure, and dry to obtain extract powder 1; add 3.3L of 65% ethanol to extract twice, each time for 2 hours, combine the extracts, and recover the ethanol Concentrate and dry to obtain extract powder 2; add 1.7L of ethyl acetate for ultrasonic extraction twice for 2 hours each time, combine the extracts, recover ethyl acetate, concentrate and dry to obtain extract powder 3, and then add 3 The extract powder is mixed evenly, 12.5 grams of menthol is added, the mixture is evenly mixed, an appropriate amount of starch is added, and the capsules are ready.

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PUM

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Abstract

The invention relates to a preparation method of a throat clearing drug. The throat clearing drug is prepared from Japanese peristrophe herb, radix ardisiae crenatae, radix adinae rubellae, roots of memorialis, radix tinosporae, radix platycodi, herba menthae and menthol, has effects of expelling wind to relieve exterior syndromes, clearing away heat and toxic materials and clearing the throat, and can effectively treat persons with symptoms such as throat pain, dry throat and hoarseness or fever with evil wind, cough and the like.

Description

technical field [0001] The invention relates to a preparation method of a throat clearing preparation, belonging to the technical field of medicine. Background technique [0002] The throat is an important immune organ of the human body, and many infectious and immune diseases are closely related to the throat. Pharyngitis is a common clinical disease and frequently-occurring disease, which is a part of upper respiratory tract infection. During acute attacks, patients often feel sore throat, accompanied by dysphagia, aphonia, pharyngeal itching, dry throat, and foreign body sensation in the pharynx. The disease is more common in adults, has a long course, and is prone to recurrence. At present, in addition to Western medicine anti-inflammatory drugs, Chinese patent medicines that clear heat and detoxify and clear the throat are often used to treat the disease, such as Golden Throat Lozenges, Throat Clear Throat Dropping Pills, and Manyan Shuning Granules. [0003] Throat ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K47/10A61K36/73A61P11/04
CPCA61K9/2031A61K36/19A61K36/185A61K36/73A61K36/59A61K36/346A61K36/534A61P11/04A61K2300/00Y02A50/30
Inventor 窦啟玲窦雅琪黄彩河陈程
Owner GUIZHOU YIBAI WOMAN BIG PHARMA FACTORY
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