Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Allopurinol quality detection method

A quality detection method, the technology of allopurinol, which is applied in the direction of measuring device, transmittance measurement, preparation of test samples, etc., can solve the problems of detection result error, etc., and achieve rapid response, convenient observation, high accuracy and sensitivity Effect

Pending Publication Date: 2020-10-02
无锡紫杉药业股份有限公司
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies of the prior art, the present invention provides a method for detecting the quality of allopurinol, mainly to solve the problem that the existing detection results have large errors and cannot meet people's requirements

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Allopurinol quality detection method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] refer to figure 1 , a kind of allopurinol quality detection method, comprises the following steps:

[0031] S1: Prepare raw materials, 30 allopurinol tablets, balance, sieve, mortar, 100 ml measuring bottle, 30 ml NaOH, 500 ml measuring bottle, 200 ml hydrochloric acid solution, stirring rod;

[0032] S2: Grinding and filtering, taking 20 allopurinol tablets, weighing with a balance, recording the mass, and then grinding with a mortar and filtering with a sieve;

[0033] S3: Dissolve, take the qualified allopurinol tablet powder after filtration and put it into a 100 ml measuring bottle, then add 20 ml of NaOH, stir with a stirring bar to make it fully dissolve, and the allopurinol to be tested can be dissolved by adding NaOH Allopurinol and other related substances, namely impurities, in the alcohol powder sample are effectively separated and detected, with strong operability, strong specificity, high accuracy and high sensitivity of the detection method;

[0034] S4...

Embodiment 2

[0041] refer to figure 1 , a kind of allopurinol quality detection method, comprises the following steps:

[0042] S1: Prepare raw materials, 30 allopurinol tablets, balance, sieve, mortar, 100 ml measuring bottle, 30 ml NaOH, 500 ml measuring bottle, 200 ml hydrochloric acid solution, stirring rod;

[0043] S2: Grinding and filtering, taking 20 allopurinol tablets, weighing with a balance, recording the mass, and then grinding with a mortar and filtering with a sieve;

[0044] S3: Dissolve, take the qualified allopurinol tablet powder after filtration and put it into a 100 ml measuring bottle, then add 20 ml of NaOH, stir with a stirring bar to make it fully dissolve, and the allopurinol to be tested can be dissolved by adding NaOH Allopurinol and other related substances, namely impurities, in the alcohol powder sample are effectively separated and detected, with strong operability, strong specificity, high accuracy and high sensitivity of the detection method;

[0045] S4...

Embodiment 3

[0052] refer to figure 1 , a kind of allopurinol quality detection method, comprises the following steps:

[0053] S1: Prepare raw materials, 30 allopurinol tablets, balance, sieve, mortar, 100 ml measuring bottle, 30 ml NaOH, 1000 ml measuring bottle, 200 ml hydrochloric acid solution, stirring rod;

[0054] S2: Grinding and filtering, taking 40 allopurinol tablets, weighing with a balance, recording the mass, and then grinding with a mortar and filtering with a sieve;

[0055] S3: Dissolve, take the qualified allopurinol tablet powder after filtration and put it into a 100 ml measuring bottle, then add 40 ml of NaOH, stir with a stirring bar to make it fully dissolve, and the allopurinol to be tested can be dissolved by adding NaOH Allopurinol and other related substances, namely impurities, in the alcohol powder sample are effectively separated and detected, with strong operability, strong specificity, high accuracy and high sensitivity of the detection method;

[0056] S...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of drug detection, and discloses an allopurinol quality detection method, which comprises: S1, preparing raw materials: 30 pieces of allopurinol tablets, abalance, a screen, a mortar, a 100 ml measuring flask, 30 ml of NaOH, a 500 ml measuring flask, 200 ml of hydrochloric acid solution, and a stirring rod; S2, carrying out grinding and filtering: weighing 20 pieces of allopurinol tablets by using the balance, recording the mass, carrying out grinding by using the mortar and filtering by using the screen; and S3, carrying out dissolution. Accordingto the method disclosed by the invention, allopurinol and other related substances, namely impurities, in the allopurinol powder sample to be detected can be effectively separated and detected; the operability is strong, the specificity of the detection method is strong, the sufficient reaction of allopurinol powder and NaOH is promoted, and the time is saved; and the liquid medicine adhered to the surface of the stirring rod can be flushed away, and in addition, the liquid splashing can be prevented from influencing the concentration of substances in the liquid medicine, and the influence onthe detection result is avoided, so that the detection precision is improved.

Description

technical field [0001] The invention relates to the technical field of drug detection, in particular to a method for detecting the quality of allopurinol. Background technique [0002] Allopurinol is a white or off-white crystalline powder, almost odorless. Allopurinol is mainly used in the inter-aggressive and chronic phases of gout. It is suitable for excessive uric acid production, allergies or ineffectiveness to uricosuric drugs, and unsuitable use of uric acid. Drugs for primary and secondary gout patients, to control hyperuricemia, can also be combined with uric acid drugs to enhance the efficacy, especially for patients with severe tophi but good renal function. [0003] Generally, allopurinol needs to be tested for its quality in the production process, and the detection method is generally spectrophotometry. In the process of this detection, steps such as sampling, dissolution, and filtration are required, but the general allopurinol quality detection method is in s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/31G01N21/59G01N1/28G01N1/34G01N1/38
CPCG01N21/314G01N21/59G01N1/286G01N1/34G01N1/38G01N2021/3155G01N2001/2866
Inventor 葛月兰文佺佺黄春
Owner 无锡紫杉药业股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com