Controllable reagent container for centrifugal micro-fluidic control and centrifugal micro-fluidic chip

Abstract

The invention relates to a controllable reagent container for centrifugal microfluidic control and a centrifugal microfluidic chip. The controllable reagent container comprises a container main body,wherein a reagent accommodating space is formed in the container main body and is provided with a release port, and an opening is formed in the reagent accommodating space; a top flange connected withthe container main body is further arranged at the opening and has a position protruding out of the container main body; and the container main body is provided with a diversion structure at the release port. The controllable reagent container has the advantages of simple structure, controllable reagent release function, suitability for batch preparation, convenience for rapid alignment and installation due to the design of the top flange, and convenience for use; firstly, reagents can be released in centrifugation, and the reagent container is applicable to both solid reagents and liquid reagents; secondly, the control of the reagent release interface can be realized in the centrifugal process without extra power or enabling, and the rotation of the chip does not need to be stopped; andfinally, various reagents can be contained, and the reagent releasing device is suitable for various steps of reagent releasing of POCT equipment.

Description

technical field [0001] The present application relates to the field of centrifugal microfluidics, in particular to a controllable reagent container and a centrifugal microfluidic chip for centrifugal microfluidics. Background technique [0002] Microfluidics (Microfluidics) generally refers to the technology of liquid manipulation inside submillimeter-scale channels, and the submillimeter scale is generally several microns to hundreds of microns. Microfluidics is a discipline that studies the flow of liquids on the submillimeter scale, and usually involves the fabrication of devices controlled by tiny liquids. It integrates the basic operating units involved in the fields of biology and chemistry, and even integrates the functions of the entire laboratory, including sampling, dilution, reaction, separation, detection, etc., on a small chip, so it is also called Lab-on-a-Chip (Lab-on-a-Chip). -a-Chip). This kind of chip is generally composed of various liquid storage pools ...

AI Technical Summary

Problems solved by technology

However, this method is only suitable for the storage of a single reagent, and the reagent should be released at the starting position of the entire detection. In contrast, the reagent release of the POCT device for sample pretreatment includes multiple steps of nucleic acid extraction and purification, and each step is Involving the release of reagents, obviously this preset method is also not applicable

[0007] Therefore, the reagent presetting of the microfluidic POCT device including the sample pretreatment process is still insufficient

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