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A sanitizer composition

A technology of composition and disinfectant, which is applied in the direction of drug combination, biocide, animal repellent, etc., and can solve the problems such as cloudiness of composition

Active Publication Date: 2020-10-16
UNILEVER IP HLDG BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The difficulty is that when alcohol is included at greater than about 60% by weight of the composition, the vitamin B3 compound or its derivatives tend to crystallize on storage and cause the composition to be hazy

Method used

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  • A sanitizer composition
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  • A sanitizer composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment A-E、1

[0072] Examples A-E, 1: Effect of the amount of non-ionic substances and alcohol included in the composition on haze

[0073] Preparation of Disinfectant Compositions

[0074] Three compositions as shown in Table 1 were prepared.

[0075] Table 1

[0076]

[0077] Measure the gray value of the above samples using the following procedure:

[0078] Apply one drop of each sample to a coverslip. They were then incubated at 24°C for 24-48 hours to monitor the formation of a white layer. The sanitizer without niacinamide (Example A) did not show any white layer, while the sanitizer with 3% Niacinamide (Example B) showed a uniform white layer. Furthermore, after the addition of Brij-35 (2%), breakup of the white layer was observed. Images of the coverslips were then taken and their gray value measured using Image J software. The higher the gray value, the hazier the product will appear.

[0079] Gray values ​​and standard deviations based on three measurements are given...

Embodiment F-J、2-4

[0087] Examples F-J, 2-4: Types of nonionic surfactants and HLB pairs of nonionic surfactants in compositions The effect of haze

[0088] The compositions shown in Table 4 below were prepared and their gray values ​​were measured, and the average values ​​of three measurements are shown in the table below.

[0089] Table 4

[0090]

[0091] A-Brij 97 is a fatty alcohol ethoxylate (unsaturated C18EO10) nonionic surfactant

[0092] B-Tween 80 is polyoxyethylene sorbitan alkyl ester (C18:1EO20) nonionic surfactant

[0093] C-Span 80 is also polyoxyethylene sorbitan alkyl ester (C18:1EO1) nonionic surfactant

[0094] The data in Table 4 above show that compositions of the invention (Examples 2-4) exhibit reduced haze due to the inclusion of the nonionic surfactant according to the invention. When containing a nonionic surfactant according to the invention (but with an HLB value outside the claimed range (Example H) or a non-claimed nonionic surfactant (Example I, J), the...

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Abstract

The invention relates to a sanitizer composition for topical use, i.e. for application onto the human skin, especially on hands for instantaneous disinfection of the body part while imparting long lasting immunity benefit. The sanitizer composition comprising high amount of alcohol and vitamin B3 compound or a derivative thereof is seen to be hazy and this problem is solved by inclusion of specific type non-ionic surfactant.

Description

technical field [0001] The present invention relates to a disinfectant composition for topical use, ie application to human skin, especially the hands, for immediate disinfection of body parts while conferring long-lasting immune benefits. Background technique [0002] A sanitizer, sometimes called a disinfectant, antiseptic, or antimicrobial, is a composition that is applied to living tissue, such as the skin, to reduce the likelihood of infection. Disinfectants are generally used to denote compositions that provide instant kill of bacteria on topical surfaces of animals or the human body, while disinfectants are generally used to kill bacteria on non-living surfaces. Disinfectants typically involve the use of alcohol-based microbicides. Disinfectants are usually formulated with little or no water. These are used by applying a few drops of the solution to a topical surface such as the hands and rubbing together. During rubbing, alcohol and other antimicrobial substances ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/67A61Q17/00A61K31/455
CPCA61K8/34A61K8/675A61K31/455A61Q17/005A61P3/02A01N31/02A01N43/34
Inventor M·A·巴帕特A·马祖姆达M·S·马塔帕蒂J·S·劳特
Owner UNILEVER IP HLDG BV