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A pharmaceutical composition for treating cervical spondylosis, its preparation method and application

A technology of cervical spondylosis and composition, applied in the field of medicine, can solve the problems of strong toxic side effects, long course of treatment, strong dependence on western medicine, etc., and achieve the effects of overcoming toxic side effects, taking conveniently, and overcoming slow onset of effects

Active Publication Date: 2022-06-07
SHANDONG MINGREN FURUIDA PHARMA
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine compound has problems such as slow onset of effect and long course of treatment in the treatment of cervical spondylosis, while Western medicine is highly dependent and often accompanied by strong toxic and side effects. One of the important subjects of research

Method used

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  • A pharmaceutical composition for treating cervical spondylosis, its preparation method and application
  • A pharmaceutical composition for treating cervical spondylosis, its preparation method and application
  • A pharmaceutical composition for treating cervical spondylosis, its preparation method and application

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Effect test

Embodiment

[0068] 1. Materials: Neck Pain Granules are taken from Shandong Mingren Freda Pharmaceutical Co., Ltd. (made from the following medicinal materials in the following weight ratios: 250 grams of Panax notoginseng, 750 grams of Chuanxiong, 500 grams of Corydalis chinensis, 1000 grams of Qianghuo, 750 grams of white peony root , Wei Lingxian 1000 grams, Pueraria 750 grams); Levetiracetam and Diclofenac sodium are commercially available.

[0069] 2. Animals: Wistar rats, weighing 180-220 g, provided by the Animal Experiment Center of Shandong University.

[0070] 3. Methods and Results

[0071] The administration prescriptions of each group of rats are shown in Table 1 below. The doses in Table 1 are the doses and volumes of single administration, and the medicines are all made of physiological saline into an equal volume of liquid and administered by intragastric administration once a day for one week. There were 6 rats in each group, half male and half female.

[0072] Table 1...

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Abstract

The invention provides a pharmaceutical composition for treating cervical spondylosis, a preparation method and application thereof, and belongs to the technical field of medicine. The active ingredients of the pharmaceutical composition include the following two parts: (1) active ingredients of traditional Chinese medicine: by weight, 1-15 parts of Panax notoginseng; 3-20 parts of Rhizoma Chuanxiong; 2-15 parts of Rhizoma Corydalis; 4-25 parts of Clematis; 3-20 parts of Pueraria lobata; 4-25 parts of notopterygium; (2) Western medicine active ingredient: levetiracetam with a weight ratio of 1:1-4 and diclofenac sodium. The present invention is an integrated traditional Chinese medicine and western medicine developed on the basis of Chinese patent CN1228071C. It has unique curative effect on treating cervical spondylosis, and the preparation process is simple, the curative effect is remarkable, the onset time is short, it is convenient to take, has no toxic and side effects, and is safe. efficient.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating cervical spondylosis and a preparation method and application thereof. Background technique [0002] The disclosure of information in this Background section is only for enhancement of understanding of the general background of the invention and should not necessarily be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person of ordinary skill in the art. [0003] Cervical radiculopathy is a common and frequently-occurring disease in orthopedics, and it is also the most common type of cervical spondylosis, accounting for about 60-70% of the incidence. The earliest concept of cervical spondylosis in modern medicine is mostly derived from cervical radiculopathy. It not only has a high incidence rate, but also often recurs and is difficult to heal. It brings a lo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/4015A61K31/196A61K36/716A61K36/71A61K36/66A61K36/48A61K36/258A61K36/237A61K36/236A61P19/08
CPCA61K36/258A61K36/236A61K36/66A61K36/71A61K36/65A61K36/716A61K36/488A61K36/237A61K31/4015A61K31/196A61P19/00A61K2236/331A61K2236/39A61K2236/333A61K2236/51A61K2300/00Y02A50/30
Inventor 刘杰张亚欣郝洪慧陈克欣江玉娟许敏高超潘瑞雪王莉
Owner SHANDONG MINGREN FURUIDA PHARMA
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